Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
용해도
DMSO(약간 용해됨), 메탄올(약간 용해됨)
산도 계수 (pKa)
12?+-.0.46(Predicted)
물리적 상태
고체
물리적 상태
단단한 모양
색상
흰색에서 황백색까지
안전
글리신,Lg-글루타Myl-S-(페닐메틸)-L-시스테인일-2-페닐-,1,3-디에틸에스테르,(2R)- C화학적 특성, 용도, 생산
개요
Ezatiostat is an inhibitor of glutathione S-transferase pi 1-1 (GSTP1-1; Ki = 0.4 μM). It is selective for GSTP1-1 over GSTα and GSTμ family GSTs (Kis = 20-75 μM). Ezatiostat also inhibits the protein-protein interaction between GSTP1-1 and JNK1. In vivo, ezatiostat (75 mg/kg) increases the number of circulating white blood cells in Gstp1 wild-type, but not Gstp1-/-, mice.
용도
Ezatiostat is a tripeptide analog of glutathione that can selectively inhibit GSTP1-1, the most prevalent Glutathione S-transferases (GST) isozyme in nonhepatic tissues, catalytic activity with minimal effect on the related GSTα and -μ families.
글리신,Lg-글루타Myl-S-(페닐메틸)-L-시스테인일-2-페닐-,1,3-디에틸에스테르,(2R)- 준비 용품 및 원자재
원자재
준비 용품
글리신,Lg-글루타Myl-S-(페닐메틸)-L-시스테인일-2-페닐-,1,3-디에틸에스테르,(2R)- 공급 업체