1,2,3,4-Tetrahydroquinoline
|
|
1,2,3,4-Tetrahydroquinoline 속성
- 녹는점
- 9-14 °C (lit.)
- 끓는 점
- 113-117 °C/10 mmHg (lit.) 249 °C (lit.)
- 밀도
- 1.061 g/mL at 25 °C (lit.)
- 굴절률
- n
20/D 1.593(lit.)
- 인화점
- 213 °F
- 저장 조건
- Keep in dark place,Sealed in dry,Room Temperature
- 물리적 상태
- 액체
- 산도 계수 (pKa)
- 5.09±0.20(Predicted)
- 색상
- 맑은 연한 노란색에서 노란색까지
- 냄새
- 디프로필렌 글리콜 중 1.00%. 꿀 사향고양이 동물 페놀릭
- 수소이온지수(pH)
- 10-11 (111g/l, H2O, 20℃)(as an emulsion)
- ?? ??
- 동물
- 수용성
- <1g/L(20℃)
- 어는점
- 11.0 to 20.0 ℃
- BRN
- 116149
- LogP
- 2.290
- CAS 데이터베이스
- 635-46-1(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | Xi,T | ||
---|---|---|---|
위험 카페고리 넘버 | 36/37/38-45 | ||
안전지침서 | 26-36/37-36-45-53 | ||
WGK 독일 | 3 | ||
TSCA | Yes | ||
HS 번호 | 29334990 | ||
기존화학 물질 | KE-33506 |
1,2,3,4-Tetrahydroquinoline C화학적 특성, 용도, 생산
화학적 성질
Clear pale yellow to yellow liquid. It is easily oxidized in air and may acquire a pale amber colour if exposed to air and daylight. Solidifies in the cold.용도
1,2,3,4-Tetrahydroquinoline is a reagent used in the synthesis of N-substituted benzoyl-1,2,3,4-tetrahydroquinolyl-1-carboxamides displaying fungicidal activity.정의
ChEBI: A member of the class of quinolines that is the 1,2,3,4-tetrahydro derivative of quinoline.Synthesis
1,2,3,4-Tetrahydroquinoline is synthesised using quinoline N-oxide as a raw material by chemical reaction. The specific synthesis steps are as follows:General procedure: In a 1.5 mL reaction vial, B(C6F5)3 (0.025 mmol, 5.0 mol %) was dissolved in chloroform (0.60 mL), towhich diethylsilane (1.75 mmol, 3.5 equiv) was added. After shaking briefly, quinolines (1a-p, 0.50 mmol, 1.0equiv) was subsequently added to the above catalyst solution under argon atmosphere. The reaction mixturewas stirred at 25-65 oC for 6-24 h for the reaction of 1a-h, and at 25-100 oC for 2-24 h for the reaction of 1i-p,then allowed to cool down to room temperature and concentrated under reduced pressure to give the crudeproduct. This reaction mixture was then treated with 0.25 N HCl ethereal solution (7 mL) and stirred at roomtemperature for 1 h to give the solid residue, which was subsequently washed with ether. The solid residue wasthen dissolved or suspended in MeOH (1.0 mL) and neutralized with Na2CO3·H2O (0.5 g) at 0 oC. After stirringfor 2 h, MeOH was removed under reduced pressure, and the neutralized reaction residue was dissolved inCH2Cl2 and washed with brine (5 mL) and water (5 mL). The crude product was then obtained from the organicphase of CH2Cl2 solution and finally purified by column chromatography on silica gel to give 2a-h(EtOAc/Hexane = 1/9) and 2i-p (EtOAc/Hexane = 3/7).
![1,2,3,4-Tetrahydroquinoline synthesis 1,2,3,4-Tetrahydroquinoline synthesis](/NewsImg/2024-02-01/6384238033079004605198852.png)
1,2,3,4-Tetrahydroquinoline 준비 용품 및 원자재
원자재
준비 용품
6-Bromoquinoline
7-아미노-1-메틸-1,2,3,4-테트라히드로퀴놀린
1,2,3,4-Tetrahydro-8-hydroxyquinoline
릴로리딘
7-니트로-퀴놀린
4-티아졸 카르복실산
1-Piperidinecarboxylic acid, 4-(3,4-dihydro-1(2H)-quinolinyl)-, 1,1-dimethylethyl ester
Quinoline, 8-ethyl-1,2,3,4-tetrahydro-
6-요오도-1,2,3,4-테트라하이드로퀴놀린
7-HYDROXY-5-OXO-N-PROPYL-2,3-DIHYDRO-1H,5H-PYRIDO[3,2,1-IJ]QUINOLINE-6-CARBOXAMIDE
1,2,3,4-Tetrahydroquinoline 공급 업체
글로벌( 424)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Handan Huajun chemicals Co.,Ltd | +86-0310-8166573 +8618630058311 |
sales@huajunchem.com | China | 29 | 58 |
Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12449 | 58 |
hebei hongtan Biotechnology Co., Ltd | +86-86-1913198-3935 +8617331935328 |
sales03@chemcn.cn | China | 973 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29798 | 60 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21668 | 55 |
career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29892 | 58 |
Zhejiang ZETian Fine Chemicals Co. LTD | +8618957127338 |
stella@zetchem.com | China | 2136 | 58 |
Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 |
sales@amoychem.com | China | 6387 | 58 |
Henan Xiangtong Chemical Co., Ltd. | 86-371-61312303 |
info@hnxtchem.com | CHINA | 292 | 58 |
Xi'an Kono chem co., Ltd., | 029-86107037 13289246953 |
info@konochemical.com | China | 2995 | 58 |
1,2,3,4-Tetrahydroquinoline 관련 검색:
8-하이드록시퀴놀린 이소퀴놀린 에톡시퀸 3,7-디클로로-8-퀴놀린카복실산 퀸하이드론 8-히드록시주로리딘 2,3,6,7-테트라하이드로-9-메틸-1H,5H,11H-[1]벤조피라노[6,7,8-ij]퀴놀리진-11-온 1-(2-히드록시에틸)-1,2,3,4-테트라히드로-2,2,4,7-테트라메틸퀴노린
QUINOLINE SULPHATE
6-HYDROXY-2-OXO-1,2,3,4-TETRAHYDROQUINOLINE (6-HQ),6-HYDROXY-2-OXO-1,2,3,4-TETRAHYDROQUINOLINE (6-HQ)
Coumarin 339
1,2,3,4-Tetrahydroquinaldine
Julolidine
CALYCANTHINE
SULFORHODAMINE 101
6-FLUORO-2-METHYL-1,2,3,4-TETRAHYDROQUINOLINE 99,6-FLUORO-2-METHYL-1,2,3,4-TETRAHYDROQUINOLINE 99
Coumarin 153
6-METHYL-1,2,3,4-TETRAHYDROQUINOLINE