Scopolamine Hydrobromide Trihydrate
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Scopolamine Hydrobromide Trihydrate 속성
- 녹는점
- 197-194 °C
- 굴절률
- -25.5 ° (C=5, H2O)
- 저장 조건
- Poison room
- 용해도
- H2O: 용해성50mg/mL
- 물리적 상태
- 결정 또는 결정성 분말
- 색상
- 흰색에서 황백색까지
- optical activity
- [α]25/D 24 to 26°, c = 5 in H2O(lit.)
- Merck
- 14,8406
- BRN
- 6100669
- 안정성
- 안정적이지만 공기와 빛에 민감합니다. 산, 염기, 강산화제와 호환되지 않습니다. 약간 흡습성이 있습니다.
- LogP
- 0.760 (est)
- CAS 데이터베이스
- 6533-68-2(CAS DataBase Reference)
안전
위험품 표기 | T+ | ||
---|---|---|---|
위험 카페고리 넘버 | 26/27/28 | ||
안전지침서 | 45-25-1 | ||
유엔번호(UN No.) | UN1544 6.1/PG 3 | ||
WGK 독일 | 1 | ||
RTECS 번호 | YM4550000 | ||
위험 등급 | 6.1 | ||
포장분류 | III | ||
HS 번호 | 29399990 |
Scopolamine Hydrobromide Trihydrate C화학적 특성, 용도, 생산
개요
Scopolamine hydrobromide is a bronchodilator indicated for the maintenance treatment of chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema, the maintenance treatment of concomitant dyspnea and the prevention of acute exacerbations.화학적 성질
white crystalline solid용도
Scopolamine is a nasal decongestant and adrenergic agonist that is used to dilate the pupil, reduce eye focusing ability, control saliva and gastric acid production, slow intestinal movements, and prevent vomiting.정의
ChEBI: Scopolamine hydrobromide trihydrate is a hydrate that is the trihydrate form of scopolamine hydrobromide. It has a role as a mydriatic agent, a muscarinic antagonist, an anaesthesia adjuvant, an antispasmodic drug and an antiemetic. It contains a scopolamine hydrobromide (anhydrous).일반 설명
White orthorhombic sphenoidal crystals from water. pH of 0.05 molar solution: 5.85.공기와 물의 반응
Is sensitive to air, light and moisture. Slightly efflorescent in dry air.반응 프로필
SCOPOLAMINE HYDROBROMIDE TRIHYDRATE is incompatible with acids, bases and oxidizing agents. .화재위험
Flash point data for SCOPOLAMINE HYDROBROMIDE TRIHYDRATE are not available. SCOPOLAMINE HYDROBROMIDE TRIHYDRATE is probably combustible.Mode of action
Scopolamine Hydrobromide[6533-68-2] is a Belladonna Alkaloid with Anticholinergic Activity. It competitively inhibits muscarinic receptors of the parasympathetic nervous system for acetylcholine and act as a nonselective muscarinic antagonist, producing peripheral anti-muscarinic, central sedative and antiemetic effects. The parasympatholytic scopolamine, structurally very similar to atropine as well, is used in conditions requiring decreased parasympathetic activity. Therefore, scopolamine can inhibit the secretion of saliva and sweat, decrease gastrointestinal secretions and motility, and increase heart rate et al.참고 문헌
[1] KLINKENBERGINGE BloklandArjan. The validity of scopolamine as a pharmacological model for cognitive impairment: a review of animal behavioral studies.[J]. Neuroscience and Biobehavioral Reviews, 2010. DOI:10.1016/j.neubiorev.2010.04.001.[2] CEYHAN T, KARTAL M, ALTUN M L, et al. LC determination of atropine sulfate and scopolamine hydrobromide in pharmaceuticals.[J]. Journal of pharmaceutical and biomedical analysis, 2001, 25 3-4: 399-406. DOI:10.1016/S0731-7085(00)00514-8.
[3] STEENKAMPP A. Fatal Datura poisoning: identification of atropine and scopolamine by high performance liquid chromatography/photodiode array/mass spectrometry.[J]. Forensic science international, 2004. DOI:10.1016/j.forsciint.2004.03.011.
[4] MUHTADI F J, HASSAN M M A. Analytical Profile Of Scopolamine Hydrobromide[C]//Vol. 19. 1990: 477-551. DOI:10.1016/S0099-5428(08)60376-7.
Scopolamine Hydrobromide Trihydrate 준비 용품 및 원자재
원자재
준비 용품
Scopolamine Hydrobromide Trihydrate 공급 업체
글로벌( 177)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Hebei Yanxi Chemical Co., Ltd. | +86-17531190177; +8617531190177 |
peter@yan-xi.com | China | 5873 | 58 |
Anhui Zhongda Biotechnology Co., Ltd | +8619956560829 |
justine@zhongda-biotech.com | China | 300 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21667 | 55 |
Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 |
admin@nexconn.com | China | 10312 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 |
sales@amoychem.com | China | 6387 | 58 |
Hebei shuoxi biotechnology co. LTD | +8613081092107 |
CHINA | 968 | 58 | |
zhangjiagang vinsce bio-pharm. limited. | 86-512-58389969 |
sales1@swellxin.com | CHINA | 111 | 58 |
WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD | +8615377521700 |
wangwendy93@gmail.com | China | 868 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
Scopolamine Hydrobromide Trihydrate 관련 검색:
Scopolamine
Methscopolamine bromide
Scopolamine butylbromide
SCOPOLAMINE N-OXIDE HYDROBROMIDE
HYOSCINE N BUTYL BROMIDE BP
Scopolamine hydrobromide
Scopine
HYOSCINE HYDROCHLORIDE
ATROPINE-D3 98 ATOM % D
Scopolamine Hydrobromide Trihydrate
ANISODAMINE HYDROBROMIDE
SCOPOLAMINE-D3 HBR 3H2O (N-METHYL-D3)
HYOSCYAMINE HYDROBROMIDE