티라민 염산염
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티라민 염산염 속성
- 녹는점
- 253-255 °C(lit.)
- 끓는 점
- 269°C/760mmHg
- 저장 조건
- Store below +30°C.
- 용해도
- H2O: 가용성 50 mg/ml, 투명, 무색 ~ 희미한 노란색
- 물리적 상태
- 결정성 분말
- 색상
- 흰색에서 거의 흰색
- 수소이온지수(pH)
- <7 (H2O)
- 감도
- Hygroscopic
- Merck
- 14,9835
- BRN
- 3627058
- 안정성
- 흡습성
- LogP
- 0.722 (est)
- CAS 데이터베이스
- 60-19-5(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xi | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 36/37/38 | ||
| 안전지침서 | 22-24/25-36-26 | ||
| WGK 독일 | 3 | ||
| RTECS 번호 | NL4375000 | ||
| F 고인화성물질 | 3-8-10 | ||
| TSCA | Yes | ||
| HS 번호 | 29222900 |
티라민 염산염 C화학적 특성, 용도, 생산
화학적 성질
Off-White to Light Yellow Powder출처
Tyramine was originally a compound isolated from ergot alkaloids and decaying animal tissue. It has pharmacological effects such as increasing blood pressure and exciting the uterus.용도
Tyramine hydrochloride is a sympathomimetic, the hydrochloride salt of the naturally-occurring monoamine derived from the amino acid tyrosine. Tyramine acts as a catecholamine releasing agent but cannot cross the blood-brain barrier. Tyramine hydrochloride is an amino acid that helps regulate blood pressure. Tyramine hydrochloride occurs naturally in the body, and it's found in certain foods.주요 응용
Tyramine hydrochloride (T-HCl) is a kind of fluorogenic substrate of peroxidase. It is a naturally occurring monoamine derived from tyrosine. Tyramine Hydrochloride has been used:coinfused with adenosine in control subjects and patients in order to reduce leg blood flow by 50% without affecting arterial blood pressure.
labelled with fluorescence dyes (Atto 488 and Atto 655) to serve as a substrate for peroxidase in immunofluorescence analysis.
used in dimethylformamide, labelled with 5-(and-6)carboxyfluorescein, succinimidyl ester/biotin to serve as a substrate for peroxidase in tyramide signal amplification.
Neurotransmitter.
Synthesis
Tyramine [2-(p-hydroxyphenyl) ethylamine], a significant metabolite of tyrosine, enzymatic synthesis of tyramine was established by two-step biocatalytic reaction. Firstly, l-tyrosine was prepared from raw pyruvate fermentation broth under the catalysis of TPL. Pyruvate fermentation broth was simply centrifuged, and then the supernatant was diluted and used as substrate to produce l-tyrosine. Secondly, l-tyrosine was collected as starting material to synthesize tyramine by immobilized TDC cells from Lactobacillus brevis. Pyridoxal phosphate was the common coenzyme for these two enzymes.Purification Methods
Crystallise the hydrochloride from EtOH by addition of diethyl ether, or from conc HCl. [Beilstein 3 II 355.]티라민 염산염 준비 용품 및 원자재
원자재
준비 용품
티라민 염산염 공급 업체
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