2-메톡시-5-설파모일벤조산
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2-메톡시-5-설파모일벤조산 속성
- 녹는점
- 220 °C
- 끓는 점
- 482.5±55.0 °C(Predicted)
- 밀도
- 1.492±0.06 g/cm3(Predicted)
- 저장 조건
- Room Temperature
- 용해도
- DMSO(약간 용해됨), 메탄올(약간 용해됨)
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 산도 계수 (pKa)
- 3.56±0.10(Predicted)
- 색상
- 흰색에서 황백색까지
- CAS 데이터베이스
- 22117-85-7(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xi | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 36/37/38 | ||
| 안전지침서 | 26-36/37/39 | ||
| 위험 참고 사항 | Irritant | ||
| HS 번호 | 2922500090 |
2-메톡시-5-설파모일벤조산 C화학적 특성, 용도, 생산
용도
2-Methoxy-5-sulfamoylbenzoic Acid is a metabolite of the antipsychotic drug, Sulpiride (S689145).제조 방법
Synthesis of 2-methoxy-5-sulfamoyl benzoic Acid: In the amination reaction of 2-methoxyl-5-amino-sulfonyl benzoic acid, the main influence factors were mainly ammonia concentration, reaction temperature and reaction time. Firstly, we investigated two approaches of animation reaction: ventilation with ammonia in solvent and ammonium hydroxide as amino-reactant and solvent. In this section, the way of ventilation with ammonia in methyl alcohol and tetrahydrofuran would cause the rapid reaction, resulting to the incomplete reaction of 2-methoxy-5-sulfamoylbenzoic acid owing to the formation of 2-methoxy-5-sulfamoyl benzoic acid coated on the surface of the reaction. On the contrary, the lab test indicated that the way of ammonium hydroxide as amino-reactant and solvent can provide better experimental results. Secondly, the reactive temperature was the more important factor. The optimized amination temperature was to 30 °C. The low temperature would result to the long amination time, whereas high temperature can result to the generation of by-product owing to the hydrolysis of sulfonyl chloride. Finally, we evaluated the effect of reaction time. The optimized reaction time was to 5 hours. The extended reaction time can’t cause the significant improvement of yield. As a consequence, the best reactive temperature was to 30 °C and the best mole ratio between 2-methoxy-5-sulfonylchlorobenzoic acid and ammonium hydroxide was to 1:20 and the best reactive time was to 5 hours. Under the best conditions, the yield can reach to 75.8%.2-메톡시-5-설파모일벤조산 준비 용품 및 원자재
원자재
준비 용품
2-메톡시-5-설파모일벤조산 공급 업체
글로벌( 175)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 |
info@dakenam.com | China | 18775 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29881 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 |
linda@hubeijusheng.com | CHINA | 22963 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 |
sales@chemdad.com | China | 39894 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 49374 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-0519-85551759 +8613506123987 |
marketing1@neostarunited.com | China | 8838 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 32165 | 58 |
| Allfluoro pharmaceutical co. ltd. | 021-26137118 +8615821363818 |
sales@allfluoro.com | China | 5790 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 |
sales@tnjchem.com | China | 34563 | 58 |
| Chemsigma International Co., Ltd. | +86-18136843612 +86-19951791336 |
info@chemsigma.com | China | 1363 | 58 |
2-메톡시-5-설파모일벤조산 관련 검색:
설파닐아미드 P-아니시딘 파라-톨루엔설폰아마이드 메톡시아세트 산 트리플르오르메톡시벤젠 아니졸 아니스알데히드 벤조니트릴 설피리드
2-Methoxybenzoic acid
4-Methoxybenzoic acid
EPA
Ascoric Acid
2,3-Dimethoxy-5-sulphamoylbenzoic acid
Ethyl 2-methoxy-5-sulfamoylbenzoate
2-METHOXY-5-SULFAMOYLBENZOIC ACID METHYL ESTER
4-Chloro-2-Methoxy-5-Sulfamoylbenzoic Acid
CHEMBRDG-BB 6629596