Bekanamycin
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Bekanamycin 속성
- 녹는점
- 178-182° (dec)
- 알파
- D18 +130° (c = 0.5 in water); D21 +114° (c = 0.98 in water)
- 끓는 점
- 580.49°C (rough estimate)
- 밀도
- 1.3771 (rough estimate)
- 굴절률
- 1.7600 (estimate)
- 저장 조건
- under inert gas (nitrogen or Argon) at 2–8 °C
- 용해도
- 산성수(약간 용해됨), 메탄올(약간 용해됨, 가열, 초음파 처리)
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 산도 계수 (pKa)
- 13.07±0.70(Predicted)
- 색상
- 크리스탈
- 안정성
- 흡습성
Bekanamycin C화학적 특성, 용도, 생산
개요
Bekanamycin, kanamycin B, was found in the culture broth of Streptomyces kanamyceticus by Umezawa et al. in 1957. It shows the same antibacterial spectrum as kanamycin but with stronger activity. The total synthesis of bekanamycin was completed by Umezawa et al. in 1968 and the knowledge gained from its synthesis was successfully applied to the synthesis of dibekacin.용도
Kanamycin B (cas# 4696-76-8) is a compound useful in organic synthesis.Antimicrobial activity
A component of the mixture of kanamycins produced by Streptomyces kanamyceticus. It is approximately twice as active as kanamycin A and is twice as toxic. It is not active against amikacin-resistant strains of MRSA. It is poorly active against Ps. aeruginosa.The pharmacokinetics and uses are similar to those of kanamycin. A 0.5% ophthalmic solution has been used to treat gonococcal ophthalmia neonatorum. It is available in Japan.
Safety Profile
Poison by intravenous route.Moderately toxic by intraperitoneal and subcutaneousroutes. When heated to decomposition it emits toxicfumes of NOx.Purification Methods
A small quantity of kanamycin B (24mg) can be purified on a small Dowex-1 x 2 column (6 x 50mm); the required fraction is evaporated to dryness and the residue crystallised from EtOH containing a small amount of H2O. [Umezawa et al. Bull Chem Soc Jpn 42 537 1969.] It has been crystallised from H2O by dissolving ~1g in H2O (3mL), adding Me2NCHO (3mL) and setting aside at 4o overnight. The needles are collected and dried to constant weight at 130o. It has also been recrystallised from aqueous EtOH. It is slightly soluble in CHCl3 and isoPrOH. [IR: Wakazawa et al. J Antibiot 14A 180, 187 1961, Ito et al. J Antibiot 17 A 189 1964, Beilstein 18 III/IV 7631.]Bekanamycin 준비 용품 및 원자재
원자재
준비 용품
Bekanamycin 공급 업체
글로벌( 140)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29897 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 |
sales@chemdad.com | China | 39916 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 49391 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 |
sales@tnjchem.com | China | 34571 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 |
1026@dideu.com | China | 9030 | 58 |
| Finetech Industry Limited | +86-27-87465837 +8618971612321 |
info@finetechnology-ind.com | China | 9625 | 58 |
| Baoji Guokang Healthchem co.,ltd | +8615604608665 15604608665 |
dominicguo@gk-bio.com | CHINA | 9427 | 58 |
| BOC Sciences | 16314854226; +16314854226 |
inquiry@bocsci.com | United States | 19743 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 |
info@dycnchem.com | China | 52861 | 58 |
Bekanamycin 관련 검색:
6-아미노 카프로산 아미카신 황산염 3-아미노페놀 황산카나마이신 글리신 아미카신 트리스(하이드록시메틸)아미노메탄
Tobramycin Impurity
3'-Deoxyneamine
4-O-[6-Amino-2-[(aminocarbonyl)amino]-2,3,6-trideoxy-α-D-ribo-hexopyranosyl]-6-O-(3-amino-3-deoxy-α-D-glucopyranosyl)-2-deoxy-D-streptamine
2,6-DiaMino-2,3,6-trideoxy-D-ribo-Hexose Dihydrochloride
Tobramycin
(1'R,3'S,3S,5R,6R)-5-AMINO-2-AMINOMETHYL-6-(4,6-DIAMINO-2,3-DIHYDROXY-CYCLOHEXYLOXY)-TETRAHYDRO-PYRAN-3,4-DIOL
Ethambutol
ALTRENOGEST
KANAMYCIN
BEKANAMYCIN SULFATE,BEKANAMYCIN SULFATE SALT
KASUGAMYCIN