MMP-3억제제VIII

MMP-3억제제VIII
MMP-3억제제VIII 구조식 이미지
카스 번호:
208663-26-7
한글명:
MMP-3억제제VIII
동의어(한글):
MMP-3억제제VIII
상품명:
MMP-3 INHIBITOR VIII
동의어(영문):
MMP3 inhibitor 2;MMP-3 INHIBITOR VIII;2-[benzyl-(4-methoxyphenyl)sulfonylamino]-N-hydroxy-4-methylpentanamide;N-HYDROXY-2(R)-[[(4-METHOXYPHENYL)SULFONYL]-[BENZYLAMINO]-4-METHYLPENTANAMIDE;Pentanamide, N-hydroxy-2-[[(4-methoxyphenyl)sulfonyl](phenylmethyl)amino]-4-methyl-
CBNumber:
CB7481925
분자식:
C20H26N2O5S
포뮬러 무게:
406.5
MOL 파일:
Mol file

MMP-3억제제VIII 속성

밀도
1.245±0.06 g/cm3(Predicted)
저장 조건
Store at -20°C
용해도
DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 10 mg/ml
물리적 상태
결정성 고체
산도 계수 (pKa)
9.13±0.40(Predicted)
안전
  • 위험 및 안전 성명
그림문자(GHS): GHS hazard pictograms
신호 어: Warning
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
예방조치문구:
NFPA 704
0
2 0

MMP-3억제제VIII C화학적 특성, 용도, 생산

개요

Matrix metalloproteinases (MMPs) belong to a family of proteases that play a crucial role in tissue remodeling and repair by degrading extracellular matrix proteins to enable cell migration. MMP-3 (also known as stromelysin-1) is thought to play a role in the vascular remodeling that occurs during aneurysm formation and may also be involved in wound repair, progression of atherosclerosis, and tumor initiation. MMP-3 inhibitor VIII is a cell permeable sulfonamide-based hydroxamic acid that binds to the active site of MMP-3 (Ki = 23 nM) and prevents its activity. This compound has also been shown to inhibit mouse macrophage metalloelastase MME/MMP-12 with an IC50 value of 13 nM.

MMP-3억제제VIII 준비 용품 및 원자재

원자재

준비 용품


MMP-3억제제VIII 공급 업체

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