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MMP-3 INHIBITOR VIII

CAS No.
208663-26-7
Chemical Name:
MMP-3 INHIBITOR VIII
Synonyms
MMP3 inhibitor 2;MMP-3 INHIBITOR VIII;2-[benzyl-(4-methoxyphenyl)sulfonylamino]-N-hydroxy-4-methylpentanamide;N-HYDROXY-2(R)-[[(4-METHOXYPHENYL)SULFONYL]-[BENZYLAMINO]-4-METHYLPENTANAMIDE;Pentanamide, N-hydroxy-2-[[(4-methoxyphenyl)sulfonyl](phenylmethyl)amino]-4-methyl-
CBNumber:
CB7481925
Molecular Formula:
C20H26N2O5S
Molecular Weight:
406.5
MDL Number:
MFCD00932464
MOL File:
Mol file
Last updated:2023-07-14 17:48:43

MMP-3 INHIBITOR VIII Properties

Density 1.245±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 10 mg/ml
form A crystalline solid
pka 9.13±0.40(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
NFPA 704
0
2 0

MMP-3 INHIBITOR VIII price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 17246 MMP-3 Inhibitor VIII ≥95% 208663-26-7 500μg $73 2024-03-01 Buy
Cayman Chemical 17246 MMP-3 Inhibitor VIII ≥95% 208663-26-7 1mg $116 2024-03-01 Buy
Cayman Chemical 17246 MMP-3 Inhibitor VIII ≥95% 208663-26-7 5mg $359 2024-03-01 Buy
American Custom Chemicals Corporation INB0001299 MMP-3 INHIBITOR VIII 95.00% 208663-26-7 5MG $498.75 2021-12-16 Buy
AK Scientific 8377CR MMP-3InhibitorVIII 208663-26-7 1mg $226 2021-12-16 Buy
Product number Packaging Price Buy
17246 500μg $73 Buy
17246 1mg $116 Buy
17246 5mg $359 Buy
INB0001299 5MG $498.75 Buy
8377CR 1mg $226 Buy

MMP-3 INHIBITOR VIII Chemical Properties,Uses,Production

Description

Matrix metalloproteinases (MMPs) belong to a family of proteases that play a crucial role in tissue remodeling and repair by degrading extracellular matrix proteins to enable cell migration. MMP-3 (also known as stromelysin-1) is thought to play a role in the vascular remodeling that occurs during aneurysm formation and may also be involved in wound repair, progression of atherosclerosis, and tumor initiation. MMP-3 inhibitor VIII is a cell permeable sulfonamide-based hydroxamic acid that binds to the active site of MMP-3 (Ki = 23 nM) and prevents its activity. This compound has also been shown to inhibit mouse macrophage metalloelastase MME/MMP-12 with an IC50 value of 13 nM.

MMP-3 INHIBITOR VIII Preparation Products And Raw materials

Raw materials

Preparation Products

MMP-3 INHIBITOR VIII Suppliers

Global( 14)Suppliers
Supplier Tel Email Country ProdList Advantage
Hangzhou MolCore BioPharmatech Co.,Ltd.
+86-057181025280; +8617767106207 sales@molcore.com China 49739 58
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 52927 58
VDM Biochemicals 0330-2528181 sales@vdmbio.com United States 510 64
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 14059 65
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8141 58
Shanghai Haohong Scientific Co., Ltd. 400-400-8210725 malulu@leyan.com China 40041 58
Nanjing Tengyi Biotechnology Co., Ltd 025-58851786 17714337195 sales@tybiochem.com China 5594 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 8739 58
MMP-3 INHIBITOR VIII N-HYDROXY-2(R)-[[(4-METHOXYPHENYL)SULFONYL]-[BENZYLAMINO]-4-METHYLPENTANAMIDE 2-[benzyl-(4-methoxyphenyl)sulfonylamino]-N-hydroxy-4-methylpentanamide Pentanamide, N-hydroxy-2-[[(4-methoxyphenyl)sulfonyl](phenylmethyl)amino]-4-methyl- MMP3 inhibitor 2 208663-26-7