MMP-3 INHIBITOR VIII
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- $73 - $498.75
- Product name: MMP-3 INHIBITOR VIII
- CAS: 208663-26-7
- MF: C20H26N2O5S
- MW: 406.5
- EINECS:
- MDL Number:MFCD00932464
- Synonyms:MMP-3 INHIBITOR VIII;N-HYDROXY-2(R)-[[(4-METHOXYPHENYL)SULFONYL]-[BENZYLAMINO]-4-METHYLPENTANAMIDE;2-[benzyl-(4-methoxyphenyl)sulfonylamino]-N-hydroxy-4-methylpentanamide;Pentanamide, N-hydroxy-2-[[(4-methoxyphenyl)sulfonyl](phenylmethyl)amino]-4-methyl-;MMP3 inhibitor 2
5 prices
Selected condition:
Brand
- AK Scientific
- American Custom Chemicals Corporation
- Cayman Chemical
Package
- 500μg
- 1mg
- 5MG
- ManufacturerAK Scientific
- Product number8377CR
- Product descriptionMMP-3InhibitorVIII
- Packaging1mg
- Price$226
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0001299
- Product descriptionMMP-3 INHIBITOR VIII 95.00%
- Packaging5MG
- Price$498.75
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number17246
- Product descriptionMMP-3 Inhibitor VIII ≥95%
- Packaging500μg
- Price$73
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17246
- Product descriptionMMP-3 Inhibitor VIII ≥95%
- Packaging1mg
- Price$116
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17246
- Product descriptionMMP-3 Inhibitor VIII ≥95%
- Packaging5mg
- Price$359
- Updated2024-03-01
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 8377CR | MMP-3InhibitorVIII | 1mg | $226 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | INB0001299 | MMP-3 INHIBITOR VIII 95.00% | 5MG | $498.75 | 2021-12-16 | Buy |
Cayman Chemical | 17246 | MMP-3 Inhibitor VIII ≥95% | 500μg | $73 | 2024-03-01 | Buy |
Cayman Chemical | 17246 | MMP-3 Inhibitor VIII ≥95% | 1mg | $116 | 2024-03-01 | Buy |
Cayman Chemical | 17246 | MMP-3 Inhibitor VIII ≥95% | 5mg | $359 | 2024-03-01 | Buy |
Properties
Density :1.245±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 10 mg/ml
form :A crystalline solid
pka :9.13±0.40(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 10 mg/ml
form :A crystalline solid
pka :9.13±0.40(Predicted)
Safety Information
Symbol(GHS): |
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Signal word: | Warning | |||||||
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Description
Matrix metalloproteinases (MMPs) belong to a family of proteases that play a crucial role in tissue remodeling and repair by degrading extracellular matrix proteins to enable cell migration. MMP-3 (also known as stromelysin-1) is thought to play a role in the vascular remodeling that occurs during aneurysm formation and may also be involved in wound repair, progression of atherosclerosis, and tumor initiation. MMP-3 inhibitor VIII is a cell permeable sulfonamide-based hydroxamic acid that binds to the active site of MMP-3 (Ki = 23 nM) and prevents its activity. This compound has also been shown to inhibit mouse macrophage metalloelastase MME/MMP-12 with an IC50 value of 13 nM.Suppliers and manufacturers
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