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ChemicalBook >> CAS DataBase List >> MMP-3 INHIBITOR VIII

MMP-3 INHIBITOR VIII

MMP-3 INHIBITOR VIII price.
  • $73 - $498.75
  • Product name: MMP-3 INHIBITOR VIII
  • CAS: 208663-26-7
  • MF: C20H26N2O5S
  • MW: 406.5
  • EINECS:
  • MDL Number:MFCD00932464
  • Synonyms:MMP-3 INHIBITOR VIII;N-HYDROXY-2(R)-[[(4-METHOXYPHENYL)SULFONYL]-[BENZYLAMINO]-4-METHYLPENTANAMIDE;2-[benzyl-(4-methoxyphenyl)sulfonylamino]-N-hydroxy-4-methylpentanamide;Pentanamide, N-hydroxy-2-[[(4-methoxyphenyl)sulfonyl](phenylmethyl)amino]-4-methyl-;MMP3 inhibitor 2
5 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • Cayman Chemical
Package
  • 500μg
  • 1mg
  • 5MG
  • ManufacturerAK Scientific
  • Product number8377CR
  • Product descriptionMMP-3InhibitorVIII
  • Packaging1mg
  • Price$226
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0001299
  • Product descriptionMMP-3 INHIBITOR VIII 95.00%
  • Packaging5MG
  • Price$498.75
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number17246
  • Product descriptionMMP-3 Inhibitor VIII ≥95%
  • Packaging500μg
  • Price$73
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17246
  • Product descriptionMMP-3 Inhibitor VIII ≥95%
  • Packaging1mg
  • Price$116
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17246
  • Product descriptionMMP-3 Inhibitor VIII ≥95%
  • Packaging5mg
  • Price$359
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 8377CR MMP-3InhibitorVIII 1mg $226 2021-12-16 Buy
American Custom Chemicals Corporation INB0001299 MMP-3 INHIBITOR VIII 95.00% 5MG $498.75 2021-12-16 Buy
Cayman Chemical 17246 MMP-3 Inhibitor VIII ≥95% 500μg $73 2024-03-01 Buy
Cayman Chemical 17246 MMP-3 Inhibitor VIII ≥95% 1mg $116 2024-03-01 Buy
Cayman Chemical 17246 MMP-3 Inhibitor VIII ≥95% 5mg $359 2024-03-01 Buy

Properties

Density :1.245±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 10 mg/ml
form :A crystalline solid
pka :9.13±0.40(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Matrix metalloproteinases (MMPs) belong to a family of proteases that play a crucial role in tissue remodeling and repair by degrading extracellular matrix proteins to enable cell migration. MMP-3 (also known as stromelysin-1) is thought to play a role in the vascular remodeling that occurs during aneurysm formation and may also be involved in wound repair, progression of atherosclerosis, and tumor initiation. MMP-3 inhibitor VIII is a cell permeable sulfonamide-based hydroxamic acid that binds to the active site of MMP-3 (Ki = 23 nM) and prevents its activity. This compound has also been shown to inhibit mouse macrophage metalloelastase MME/MMP-12 with an IC50 value of 13 nM.