SHU-9119
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SHU-9119 속성
- 밀도
- 1.43±0.1 g/cm3(Predicted)
- 저장 조건
- -20°C
- 용해도
- H2O : 20 mg/mL (18.62 mM; Need ultrasonic)
- 물리적 상태
- 가루
- 산도 계수 (pKa)
- 13.00±0.70(Predicted)
- 색상
- White to off-white
- 수용성
- Soluble to 0.20 mg/ml in water
- 시퀀스
- Ac-Nle-Asp-His-D-Nal-Arg-Trp-Lys-NH2(Chemical Bridge Asp2-Lys7)
안전
WGK 독일 | 3 |
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SHU-9119 C화학적 특성, 용도, 생산
개요
SHU9119 is an agonist of melanocortin receptor 1 (MC1R) and antagonist of MC4R (IC50s = 1.2 and 2.9 nM, respectively, for displacement of melanocortin). It induces cAMP formation in HEK293 cells expressing human MC1R (EC50 = 1.11 nM), but inhibits cAMP formation in cells expressing human MC4R. In rats, SHU9119 (24 nmol, i.c.v. per day for seven days) increases food intake, body weight, fat mass, and lean mass, with concomitant increases in blood glucose, insulin, and leptin levels via disrupted melanocortin signaling. Similarly, mice treated with SHU9119 (5 nmol/day, i.c.v.) exhibit food intake-independent increases in body weight and fat mass consequent to MC4R inhibition and subsequent brown adipose tissue dysfunction.SHU-9119 준비 용품 및 원자재
원자재
준비 용품
SHU-9119 공급 업체
글로벌( 91)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Alpha Biopharmaceuticals Co., Ltd | +86-15542445688 |
sales@alabiochem.com | China | 888 | 58 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 |
info@dakenam.com | China | 18642 | 58 |
Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 |
admin@nexconn.com | China | 10311 | 58 |
Cellmano Biotech Limited | 0551-65326643 18156095617 |
info@cellmano.com | China | 999 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
Career Henan Chemica Co | +86-0371-86658258 +8613203830695 |
laboratory@coreychem.com | China | 30250 | 58 |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 |
sales@sarms4muscle.com | China | 10522 | 58 |
Nextpeptide Inc | +86-0571-81612335 +8613336028439 |
sales@nextpeptide.com | China | 19915 | 58 |
Chengdu Youngshe Chemical Co., Ltd. | +8618108235634 |
Cecilia@youngshechem.com | China | 2345 | 58 |
Nanjing TGpeptide | +86-13347807150 +86-13347807150 |
support@tgpeptide.com | China | 3279 | 58 |