4-(p-Methoxyphenyl)-2-butanone has an intensely sweet, floral,
fruity odor and a cherry-raspberry flavor at low concentrations.
May be prepared by condensing acetone with anisaldehyde to yield anisylidene acetone and subsequent hydrogenation in the presence
of Pd catalyst.
화학적 성질
4-(4-Methoxyphenyl)-2-butanone is a clear colourless to pale yellow liquid. B.P. 277℃. Solidifies
in the cold, melts again at 10℃. Very slightly soluble in water, soluble in
alcohol and oils, poorly soluble in Propylene
glycol. Intensely sweet, floral and slightly fruity,
Cherry-preserve-like odor of good tenacity.
It has considerable resemblance to Heliotropine in its overall performance in a composition. Pleasant, sweet-fruity, Cherry-Raspberry-type flavor at concentrations below 40 ppm.
Tends to appear "perfumey" at levels higher
than 100 ppm.
출처
Contained (approximately 53% level) in the odorous principle obtained by extraction and hydrolysis from aloe
wood (Aquilaria algallocha Roxb.) and in anise.
용도
4-(4-Methoxyphenyl)-2-butanone is used as pharmaceutical intermediate.
제조 방법
By condensing acetone with anisaldehyde to yield anisylidene acetone and subsequent hydrogenation in the presence of
Pd catalyst. It can also be prepared from Methyl vinyl
ketone by catalytic condensation with Phenol,
followed by Methylation.
Safety Profile
Low oral and skin
toxicity. A flammable liquid. When heated
to decomposition it emits acrid smoke and
irritating fumes.
