판토프라졸
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판토프라졸 속성
- 녹는점
- 139-140° (dec)
- 끓는 점
- 586.9±60.0 °C(Predicted)
- 밀도
- 1.51±0.1 g/cm3(Predicted)
- 저장 조건
- Inert atmosphere,Store in freezer, under -20°C
- 용해도
- 클로로포름(약간 용해됨), 메탄올(약간 용해됨, 가열, 초음파 처리)
- 산도 계수 (pKa)
- pKa1 3.92; pKa2 8.19(at 25℃)
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 색상
- 미색에서 옅은 오렌지색까지
- BCS Class
- 3
- InChI
- InChI=1S/C16H15F2N3O4S/c1-23-13-5-6-19-12(14(13)24-2)8-26(22)16-20-10-4-3-9(25-15(17)18)7-11(10)21-16/h3-7,15H,8H2,1-2H3,(H,20,21)
- InChIKey
- IQPSEEYGBUAQFF-UHFFFAOYSA-N
- SMILES
- C1(S(CC2=NC=CC(OC)=C2OC)=O)NC2=CC(OC(F)F)=CC=C2N=1
- CAS 데이터베이스
- 102625-70-7(CAS DataBase Reference)
안전
- 위험 및 안전 성명
| 위험품 표기 | Xn | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 20/21/22-37/38-41-48 | ||
| 안전지침서 | 22-26-36/37/39-45 | ||
| 유해 물질 데이터 | 102625-70-7(Hazardous Substances Data) |
판토프라졸 C화학적 특성, 용도, 생산
개요
Pantoprazole, an irreversible proton pump inhibitor, reached its first market worldwide in Germany for acute treatment of gastric and duodenal ulcers and gastroesophageal reflux disease. Proton pump inhibitors are more effective than other strategies in inhibiting acid secretion since they function at the final step of acid production, therefore, provide superior symptom relief and healing in all acid related diseases. As the third substituted benzimidazole proton pump inhibitor marketed, pantoprazole not only has superior ulcer-preventing effect but also is more potent than omeprazole in healing acetic acid-induced gastric and duodenal ulcers with extremely low acute toxicity. The mechanism of action for this class of compounds has been suggested to be mediated via the protonated form of the molecule which selectively reacts with cysteines present on the extracytoplasmic face of the enzyme to form covalent disulfide bonds.용도
proton pump inhibitor, gastric acid release inhibitor, antiulcer정의
ChEBI: A member of the class of benzimidazoles that is 1H-benzimidazole substituted by a difluoromethoxy group at position 5 and a [(3,4-dimethoxypyridin-2-yl)methyl]sulfinyl group at position 2.판토프라졸 준비 용품 및 원자재
원자재
2-mercapto-5-difluoromethoxy-1H-benzimidazole
3-클로로페록시벤조산
피리딘,3,4-디메톡시-(9CI)
5-(Difluoromethoxy)-1H-Benzimidazole-2-thiol
수산화나트륨
차아염소산나트륨
티오황산 나트륨
준비 용품
판토프라졸 공급 업체
글로벌( 246)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 +86-17331933971 |
deasea125996@gmail.com | China | 2503 | 58 |
| Sigma Audley | +86-15937194204 +86-18126314766 |
nova@sh-teruiop.com | China | 491 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21667 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 |
product@chemlin.com.cn | CHINA | 3012 | 60 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 49392 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 |
factory@coreychem.com | China | 29825 | 58 |
| Wuhan Monad Medicine Tech Co.,LTD | 02768782018 18771942761 |
sales01@whmonad.com | CHINA | 992 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 |
sales@hzclap.com | CHINA | 6313 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 |
eric@witopchemical.com | China | 23556 | 58 |
판토프라졸 관련 검색:
아니스일 알코올 (4-메톡시페닐)아세토나이트릴 P-아니시딘 트리플르오르메톡시벤젠 4-메톡시페놀 과이아콜 아니졸 아니스알데히드
Pantoprazole Sodium
4-Methoxybenzoic acid
PANTOPRAZOLE SULPHONE SODIUM SALT
Rabeprazole
Omeprazole
R-(+)-Lansoprazole
5-Difluoromethoxy-2-mercapto-1H-Benzimidazole(Pantoprazole Intermediate
Intermediate of pantoprazole sodium
2-chloromethyl-3,4-dimethoxy pyridine HCL (intermediate of pantoprazole),Pantoprazole Intermediate
2-CHLOROMETHYL-3,4-DIMETHOXY PYRIDINE HYDROCHLORIDE