시안초산
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시안초산 속성
- 녹는점
- 65 °C
- 끓는 점
- 108 °C0.15 mm Hg(lit.)
- 밀도
- 1.3676 (rough estimate)
- 증기압
- 0.1 mm Hg ( 100 °C)
- 굴절률
- 1.3764 (estimate)
- 인화점
- 226 °F
- 저장 조건
- Store below +30°C.
- 용해도
- H2O: 가용성 50mg/mL, 투명, 무색에서 매우 희미한 노란색
- 산도 계수 (pKa)
- 2.45(at 25℃)
- 물리적 상태
- 결정질 고체 부착
- 색상
- 흰색~밝은 베이지
- 수소이온지수(pH)
- 1.6 (50g/l, H2O, 20℃)
- 수용성
- 1000g/L(20℃)
- 감도
- Hygroscopic
- Merck
- 14,2689
- BRN
- 506325
- Dielectric constant
- 33.0（4℃）
- InChIKey
- MLIREBYILWEBDM-UHFFFAOYSA-N
- LogP
- -0.76
- CAS 데이터베이스
- 372-09-8(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | C | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 22-31-34-52/53-20/22 | ||
| 안전지침서 | 26-36/37/39-45-61-20 | ||
| 유엔번호(UN No.) | UN 3261 8/PG 2 | ||
| WGK 독일 | 2 | ||
| RTECS 번호 | AG3675000 | ||
| F 고인화성물질 | 3-10-21 | ||
| TSCA | Yes | ||
| HS 번호 | 2926 90 70 | ||
| 위험 등급 | 8 | ||
| 포장분류 | II | ||
| 유해 물질 데이터 | 372-09-8(Hazardous Substances Data) | ||
| 독성 | LD50 orally in Rabbit: 1500 mg/kg LD50 dermal Rabbit > 2000 mg/kg | ||
| 기존화학 물질 | KE-09029 |
시안초산 C화학적 특성, 용도, 생산
개요
Cyanoacetic acid is an organic compound. It is a white, hygroscopic solid. The compound contains two functional groups, a nitrile (C≡N) and a carboxylic acid. It is a precursor to cyanoacrylates, components of adhesives.Cyanoacetic acid is used in pharmaceutical industry for producing vitamin B6 and caffeine. It is also used in making dyes, agricultural chemicals, and in the synthesis of phenylacetic acid esters. It acts as a precursor cyanoacrylates viz. ethyl cyanoacrylate.
화학적 성질
white to light beige adhering crystalline solid용도
Cyanoacetic acid was used in the synthesis of N-piperidine-cyanacetamide and N-morpholyl-cyanacetamide. It was also used in the preparation of a panchromatic dye for dye-sensitized solar cells.정의
ChEBI: A monocarboxylic acid that consists of acetic acid bearing a cyano substituent.주요 응용
Cyanoacetic acid can be used as a reagent:Along with acetic anhydride for cyanoacetylation of various pyrroles, indoles, and aniline derivatives. It can also be used in other reactions such as cyclizations, syntheses of coumarins and other heterocycles.
To prepare of key intermediate via Knoevenagel condensation in the total synthesis of 5-acetamido-substituted melatonin derivatives as MT3 receptor ligands.
In the synthesis of aminopyrrolinone derivatives by reacting Ugi adducts of cyanoacetic acid and aromatic aldehydes.
제조 방법
Cyanoacetic acid is prepared by treatment of chloroacetate salts with sodium cyanide followed by acidification. Electrosynthesis by cathodic reduction of carbon dioxide and anodic oxidation of acetonitrile also affords cyanoacetic acid.일반 설명
Yellow-brown liquid with an unpleasant odor. Sinks and mixes with water.공기와 물의 반응
Water soluble.반응 프로필
White, moderately toxic solid, combustible. When heated to decomposition Cyanoacetic acid emits toxic fumes of nitrile and oxides of nitrogen. A stirred mixture with furfuryl alcohol exploded violently upon heating [MCA Case History No 858].건강위험
Contact irritates eyes and may irritate skin.화재위험
Special Hazards of Combustion Products: Toxic oxides of nitrogen and toxic and flammable acetonitrile vapors may form in fire.Purification Methods
Recrystallise the acid to constant melting point from *benzene/acetone (2:3), and dry it over silica gel. [Beilstein 2 H 583, 2 I 253, 2 II 530, 2 III 1626, 2 IV 1888.]시안초산 준비 용품 및 원자재
원자재
준비 용품
엔프로필라인
카페인
3,3,3-트리스(4-클로로페닐)프로피온산
2-cyano-N-methyl-N-[(methylamino)carbonyl]acetamide
1-메틸-4-[3,3,3-트리스(4-클로로페닐)프로피오닐]피페라진
2-시아노-N-[(에틸아미노)카르보닐]아세트아미드
술린다크
말론산 디메틸
3,3,3-트리스(p-클로로페닐)프로피오닐클로라이드
4-피리딘-2-일리속사졸-5-아민
5,6-Diamino-1,3-dimethyluracil hydrate
사이목사닐
6-AMINO-1,3-DIMETHYL-5-NITROSOURACIL
2,4-Dichloro-5-cyanopyrimidine
2,2-디브로모-3-니트릴로프로피온아미드
Octyl cyanoacetate
디클로로아세토니트릴
말론 산, 디나트륨 염
말론산 디에틸
말론산
에틸 사이아노아세테이트
시안초산 공급 업체
글로벌( 416)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Hebei Weibang Biotechnology Co., Ltd | +8615531157085 |
abby@weibangbio.com | China | 8807 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 |
sales@capot.com | China | 29791 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 |
info@dakenam.com | China | 18751 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21634 | 55 |
| Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 |
jack.li@time-chemicals.com | China | 1803 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32956 | 60 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +8618949832763 |
info@tnjchem.com | China | 2986 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29880 | 58 |
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 |
sales@ansciepchem.com | CHINA | 4241 | 58 |
| Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 |
sales@finerchem.com | China | 2957 | 58 |