AG 1478
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AG 1478 속성
- 녹는점
- 180 - 183°C
- 저장 조건
- 2-8°C
- 용해도
- 0.1M HCl: 가용성 <0.4mg/mL
- 물리적 상태
- 담황색 고체
- 색상
- 회백색
- 안정성
- 제공된 대로 구매일로부터 1년 동안 안정적입니다. DMSO 또는 에탄올 용액은 -20°에서 최대 3개월 동안 보관할 수 있습니다.
AG 1478 C화학적 특성, 용도, 생산
용도
Tyrphostin AG 1478 is a potent and selective inhibitor of EGFR.일반 설명
Highly potent and specific inhibitor of the epidermal growth factor (EGF) receptor tyrosine kinase (IC50 = 3 nM). Much higher concentrations are required for inhibition of the kinase activity of the closely related HER2 (neu/erb-B2) receptor (IC50 >100 μM), the platelet-derived growth factor (PDGF) receptor (IC50 >100 μM), and p210Bcr-Abl (IC50 >50 μM). Its mechanism of inhibition likely mimics that of the related compound, 4-(3-chloroanilino)quinazoline (CAQ), a competitive inhibitor with respect to ATP.Biochem/physiol Actions
Primary TargetEpidermal growth factor receptor kinaseAG 1478 준비 용품 및 원자재
원자재
준비 용품
AG 1478 공급 업체
글로벌( 115)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
Alchem Pharmtech,Inc. | 8485655694 |
sales@alchempharmtech.com | United States | 63711 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 49391 | 58 |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 |
1026@dideu.com | China | 24407 | 58 |
Amadis Chemical Company Limited | 571-89925085 |
sales@amadischem.com | China | 131980 | 58 |
J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 |
jkinfo@jkchemical.com | China | 96815 | 76 |
Shanghai Paulshine Chemical Co., Ltd. | +86-021-37788663 |
China | 186 | 64 | |
Jinan Trio PharmaTech Co., Ltd. | +86 (531) 88811783 |
sales@trio-pharmatech.com (International market) | China | 1856 | 62 |
Spectrum Chemical Manufacturing Corp. | 021-021-021-67601398-809-809-809 15221380277 |
marketing_china@spectrumchemical.com | China | 9664 | 60 |
UHN Shanghai Research & Development Co., Ltd. | 021-58958002 18930822973 |
SALES@UHNSHANGHAI.COM | China | 977 | 58 |
AG 1478 관련 검색:
Adapalene
ZM 336372
(E)-3-[[[3-[2-(7-CHLORO-2-QUINOLINYL)ETHENYL]PHENYL]-[[(3-DIMETHYLAMINO)-3-OXOPROPYL]THIO]METHYL]THIO]-PROPANOIC ACID, SODIUM SALT
Sunitinib Malate
RANAKININ
NS-398
AG 213
Quinazoline
AG 1478 in Solution
AG1478HCl,AG-1478,AG 1478 HYDROCHLORIDE
Tyrphostin AG 1478 (4-(3-Chloroanilino)-6, 7-dimethoxyquinazoline)
AG 1478 EPIDERMAL GROWTH FACT