4-[3-(5-BROMO-2-PROPOXYPHENYL)-5-(4-CHLOROPHENYL)-1H-PYRROL-2-YL]PYRIDINE
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4-[3-(5-BROMO-2-PROPOXYPHENYL)-5-(4-CHLOROPHENYL)-1H-PYRROL-2-YL]PYRIDINE 속성
- 끓는 점
- 542.3±50.0 °C(Predicted)
- 밀도
- 1.367±0.06 g/cm3(Predicted)
- 저장 조건
- Store at RT
- 용해도
- Soluble to 100 mM in DMSO and to 100 mM in ethanol
- 물리적 상태
- 라이트 베이지 솔리드
- 산도 계수 (pKa)
- 13.99±0.50(Predicted)
안전
4-[3-(5-BROMO-2-PROPOXYPHENYL)-5-(4-CHLOROPHENYL)-1H-PYRROL-2-YL]PYRIDINE C화학적 특성, 용도, 생산
용도
L- is a potent (Kb = 25 nM), selective antagonist of glucagon.생물학적 활성
Very potent and selective, non-competitive antagonist of the human glucagon receptor (hGR). Binds with high affinity to human GR (IC 50 = 3.7 nM), and moderate affinity to murine and canine GRs (IC 50 values are 63 and 60 nM respectively). In contrast, displays poor affinity for rat, guinea pig, and rabbit glucagon receptors (IC 50 > 1 μ M). In functional studies, inhibits glucagon-stimulated cAMP synthesis in CHO cells expressing hGR (IC 50 = 41 nM), and in murine liver membranes. Orally active in vivo .4-[3-(5-BROMO-2-PROPOXYPHENYL)-5-(4-CHLOROPHENYL)-1H-PYRROL-2-YL]PYRIDINE 준비 용품 및 원자재
원자재
준비 용품
4-[3-(5-BROMO-2-PROPOXYPHENYL)-5-(4-CHLOROPHENYL)-1H-PYRROL-2-YL]PYRIDINE 공급 업체
글로벌( 24)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32715 | 60 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 |
sales@aladdinsci.com | United States | 57511 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 |
3bsc@sina.com | China | 15848 | 69 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 |
China | 4196 | 55 | |
| EMMX Biotechnology LLC | 888-539-0666 |
info@emmx.com | United States | 8449 | 60 |
| Shanghai Rechem science Co., Ltd. | 21-31433387 15618786686 |
sales@rechemscience.com | China | 2994 | 58 |
| Shanghai Chaolan Chemical Technology Center | QQ:65489617 15618227136 |
info@SuperLan-chem.com | China | 9854 | 58 |
| Shanghai Changyu Medical Technology Co. Ltd. | +86-13301875428 |
sales@changyuhe.com | China | 294 | 58 |
| Changzhou Chenhong Biotechnology Co., Ltd. | 0519-85788828 13775037613 |
sales@chemrenpharm.com | China | 3574 | 58 |