Nisoxetine

Nisoxetine 구조식 이미지
카스 번호:
53179-07-0
상품명:
Nisoxetine
동의어(영문):
Nisoxetine;Compound 89218;Benzenepropanamine, γ-(2-methoxyphenoxy)-N-methyl-;[3-(2-Methoxy-phenoxy)-3-phenyl-propyl]-methyl-amine
CBNumber:
CB91179324
분자식:
C17H21NO2
포뮬러 무게:
271.36
MOL 파일:
53179-07-0.mol

Nisoxetine 속성

끓는 점
404.8±40.0 °C(Predicted)
밀도
1.054±0.06 g/cm3(Predicted)
산도 계수 (pKa)
10.16±0.10(Predicted)
물리적 상태
Viscous Liquid
색상
Colorless to light yellow

안전

Nisoxetine C화학적 특성, 용도, 생산

용도

Antidepressant.

일반 설명

Nisoxetine is a SNERI and is an antidepressant. Most activityresides in the β-isomer.

Clinical Use

Nisoxetine was the initial phenoxyphenylpropylamine synthesized in the Lilly research laboratories during the early 1970s from the rearrangement of an oxygen atom in diphenyhydramine, a diphenylmethoxyethylamine, to a phenoxyphenylpropylamine. Nisoxetine was discovered to be a potent and very selective SNRI, with little affinity for other receptors. It underwent clinical studies as an alternative to Lilly's best-selling antidepressant, nortriptyline, but without the adverse effects associated with the tricyclic secondary amines. It was never marketed, however, because of a greater interest in developing its 4-trifluoromethyl analogue, fluoxetine, an SSRI.

Nisoxetine 준비 용품 및 원자재

원자재

준비 용품


Nisoxetine 공급 업체

글로벌( 6)공급 업체
공급자 전화 이메일 국가 제품 수 이점
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795
ivan@atkchemical.com China 32760 60
Shanghai Chaolan Chemical Technology Center QQ:65489617 15618227136
info@SuperLan-chem.com China 9874 58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd 024-024-88590548 18341751992
757984502@qq.com China 892 58
TargetMol Chemicals Inc. 15002134094
marketing@targetmol.cn China 28118 58

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