SU 6668
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SU 6668 속성
- 저장 조건
- +2C to +8C
- 용해도
- DMSO : 50 mg/mL (161.11 mM; Need ultrasonic)
- 물리적 상태
- 진한 노란색 고체
- 색상
- Orange to red
안전
SU 6668 C화학적 특성, 용도, 생산
용도
PDGFR Tyrosine Kinase Inhibitor VI, SU6668 is a potent ATP-competitive inhibitor against tyrosine kinases.일반 설명
A cell-permeable indolinone compound that acts as a potent ATP-competitive inhibitor against RTKs (receptor tyrosine kinases) Kit, PDGFRβ, VEGFR2 (Flk-1/KDR), FGFR1 activity in vitro (IC50 = 0.01, 0.1, 3.9, and 3.8 μM, respectively) and PDGF/VEGF/bFGF-mediated angiogenesis and tumor development in vivo. Although initially characterized as an RTK inhibitor, SU6668 is now also known to target ser/thr kinases Aurora A, Aurora B, TBK1 (NAK/T2K), and AMPK (IC50 = 0.85, 0.047, 1.4, and 1.8 μM, respectively), as well as non-receptor TKs Lyn and Yes (IC50 = 4.3 and 5.8 μM, respectively).SU 6668 준비 용품 및 원자재
원자재
준비 용품
SU 6668 공급 업체
글로벌( 48)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Baoji Guokang Healthchem co.,ltd | +8615604608665 15604608665 |
dominicguo@gk-bio.com | CHINA | 9427 | 58 |
| Shaoxin Catsyn Co., Ltd. | +undefined-0575-82040869 +86-0575-82040869; |
sales@catsyn.com | China | 6116 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 |
sales@aladdinsci.com | United States | 52927 | 58 |
| Amadis Chemical Company Limited | 571-89925085 |
sales@amadischem.com | China | 131980 | 58 |
| Shanghai Boyle Chemical Co., Ltd. | |
sales@boylechem.com | China | 2923 | 55 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 |
info@chemlin.com.cn | China | 18089 | 64 |
| Nanjing JinruiJiuAn Biotechnology Co., Ltd. | 025-58196018 800028039 |
sales@fartop.net | China | 2231 | 55 |
| Sigma-Aldrich | 021-61415566 800-8193336 |
orderCN@merckgroup.com | China | 51471 | 80 |
| SPIRO PHARMA | |
eric_feng1954@126.com | China | 9254 | 55 |
| Nanjing River Chemical Co., Ltd. | 13951936332 18305166317 |
info@serpharm.com | China | 494 | 55 |