L-피로글루탐 산
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L-피로글루탐 산 속성
- 녹는점
- 160-163 °C(lit.)
- 끓는 점
- 239.15°C (rough estimate)
- 알파
- -27.5 º (c=10, 1 N NaOH)
- 밀도
- 1.3816 (rough estimate)
- 증기압
- 0.002Pa at 25℃
- 굴절률
- -10 ° (C=5, H2O)
- 저장 조건
- 2-8°C
- 용해도
- H2O: 1 M at 20 °C, 투명, 무색
- 물리적 상태
- 결정성 분말
- 산도 계수 (pKa)
- 3.32(at 25℃)
- 색상
- 흰색에서 황백색까지
- 수소이온지수(pH)
- 1.7 (50g/l, H2O, 20℃)
- 냄새
- 백색 결정, 무취, 약간 신맛
- optical activity
- [α]20/D 10.5±1°, c = 5% in H2O
- 수용성
- 10-15 g/100 mL (20 ºC)
- Merck
- 14,8001
- BRN
- 82132
- 안정성
- 안정적인. 염기, 산, 강산화제와 호환되지 않습니다.
- LogP
- -1.233 at 20℃
- CAS 데이터베이스
- 98-79-3(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | Xi | ||
---|---|---|---|
위험 카페고리 넘버 | 36/37/38 | ||
안전지침서 | 26-36-37/39 | ||
WGK 독일 | 3 | ||
RTECS 번호 | TW3710000 | ||
F 고인화성물질 | 21 | ||
TSCA | Yes | ||
위험 등급 | IRRITANT | ||
HS 번호 | 29337900 | ||
기존화학 물질 | KE-29979 |
L-피로글루탐 산 C화학적 특성, 용도, 생산
화학적 성질
L-pyroglutamic acid has its scientific name being L-2-pyrrolidone-5-carboxylic acid. Precipitation from ethanol and petroleum ether mixture were colorless orthorhombic bipyramid crystals with the melting temperature being 162~163 °C. It is soluble in water, alcohol, acetone and acetic acid, slightly soluble in ethyl acetate, and insoluble in ether. Specific rotation-11.9 ° (c = 2, H2O). It is produced from 42% aqueous solution of glutamic acid which subjects to heating dehydration, concentration, crystallization, washing and drying to obtain L-pyroglutamic acid.용도
L-Pyroglutamic acid is an amino acid that is used in the synthesis of peptides. It has also been observed to convert when placed at the N-terminus in vivo to create IgG2 antibodies.정의
ChEBI: An optically active form of 5-oxoproline having L-configuration.Purification Methods
Crystallise S-pyroglutamic acid by dissolving it in boiling EtOH (20g in 100mL), cooling and after a few minutes additing pet ether (b 40-60o, 120mL), then after 5 minutes adding a further 120mL, and coThis has m 155.5-157.5o and [] D -11.4o (c 4.4, H2O) [Hardy Synthesis 290 1978, Pellegata et al. Synthesis 614 1978]. The NH4 salt has m 184-186o (from EtOH). [Beilstein 22/6 V 7.]L-피로글루탐 산 준비 용품 및 원자재
원자재
준비 용품
sodium pyrrolidone carbonate
5-(AMINOMETHYL)-1-METHYLPYRROLIDIN-2-ONE
D-Pyroglutamic acid
Z-PYR-OH
2-피롤리딘메탄올,4-하이드록시-,염산염(1:1),(2S,4R)-
Pidotimod
(S)-(+)-5-(Hydroxymethyl)-2-pyrrolidinone p-toluenesulfonate
L-Pyroglutamamide
(+)-(3R,7aS)-Tetrahydro-3-phenyl-3H,5H-pyrrolo1,2-coxaole-5-one
AT-406
(S)-1-Boc-2,3-디히드로-2-피롤카르복실산에틸에스테르
피도벤존
L-글루타민 산, 염산
L-피로글루탐 산 공급 업체
글로벌( 717)공급 업체
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