Pidotimod, a dipeptide immunomodulating agent, has been introduced as
immunostimulant therapy in patients with cell-mediated immunosuppression during respiratory
or urinary tract infections. Its mode of action on the immune system is by activation of
T-lymphocytes via interleukin (IL)-2 stimulation and macrophages via activation of superoxide
dismutase and chemotaxis. In mice, treatment with pidotimod causes significant increase in
the natural killer cell activity that may play an important role in immunosurveillance against
tumors and in physiological homeostasis. Pidotimod can reverse the immunosuppression
caused by surgical stress and has antiinflammatory, antioxidant, and antiaging properties. It
has also been reported to provide protection from bacterial infections in mice.
화학적 성질
White Solid
용도
Immunostimulant used in patients with cell-mediated immunodepression.