ChemicalBook >제품 카탈로그 >D-아르기닐-2,6-디메틸-L-티로실-L-리실-L-페닐알라닌미드

D-아르기닐-2,6-디메틸-L-티로실-L-리실-L-페닐알라닌미드

D-아르기닐-2,6-디메틸-L-티로실-L-리실-L-페닐알라닌미드 구조식 이미지

카스 번호:: 736992-21-5

한글명:: D-아르기닐-2,6-디메틸-L-티로실-L-리실-L-페닐알라닌미드

동의어(한글):: D-아르기닐-2,6-디메틸-L-티로실-L-리실-L-페닐알라닌미드

상품명:: Elamipretide

동의어(영문):: MTP-131;Centanafadine;SS-31, Elamipretide;Elamipretide acetate;RX-31;SS-31);Bendavia);Elamipretide;ELAMIPRETIDE, >99%;Elamipretide (SS-31

CBNumber:: CB92708860

분자식:: C32H49N9O5

포뮬러 무게:: 639.79

MOL 파일:: 736992-21-5.mol

속성

안전

용도

공급 업체 121

D-아르기닐-2,6-디메틸-L-티로실-L-리실-L-페닐알라닌미드 속성

밀도: 1.34±0.1 g/cm3(Predicted)

용해도: 메탄올(약간 용해됨), 물(약간 용해됨)

산도 계수 (pKa): 10.10±0.25(Predicted)

물리적 상태: 고체

물리적 상태: 단단한 모양

색상: 흰색에서 황백색까지

시퀀스: H-d-Arg-dimethylTyr-Lys-Phe-NH2

안정성: 흡습성

InChIKey: SFVLTCAESLKEHH-WKAQUBQDSA-N

SMILES: C(N)(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC1=C(C)C=C(O)C=C1C)NC(=O)[C@@H](CCCNC(N)=N)N

안전

D-아르기닐-2,6-디메틸-L-티로실-L-리실-L-페닐알라닌미드 C화학적 특성, 용도, 생산

Mechanism of action

Elamipretide can inhibit the production of pathogenic ROS (reactive oxygen species) and restore mitochondrial ATP synthesis. Currently, the most accepted mechanism for these two actions is the direct interaction between Elamipretide and cardiolipin.

Clinical Use

Barth syndrome is an ultra-rare genetic condition characterized by cardiac abnormalities leading to exercise intolerance, muscle weakness, debilitating fatigue, heart failure, recurrent infections, and delayed growth. There are currently no FDA- or EMA-approved therapies for patients with Barth syndrome. Elamipretide has an Orphan Drug, Fast Track and Rare Pediatric Designation from the FDA and Orphan Drug Designation from the EMA for treating Barth syndrome.

부작용

Side effects of elamipretide include:
Mild redness or itching at the injection site
Headache
Dizziness

D-아르기닐-2,6-디메틸-L-티로실-L-리실-L-페닐알라닌미드 준비 용품 및 원자재

원자재

준비 용품

D-아르기닐-2,6-디메틸-L-티로실-L-리실-L-페닐알라닌미드 공급 업체

글로벌( 121)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Apeloa production Co.,Limited	+8619933239880	admin@apcl.com.cn	China	853	58
Shandong Huisheng Import & Export Co., Ltd.	+86-13176845580 +86-13176845580	da@zhongda-biotech.com	China	248	58
Zhejiang Hangyu API Co., Ltd	+8617531972939	anna@api-made.com	China	2944	58
Shaanxi TNJONE Pharmaceutical Co., Ltd	+8618092446649	sarah@tnjone.com	China	1143	58
Qingdao Xinli Technology Development Co., Ltd.	+8616632313095	xinlikeji01@qdxlchem.com	China	134	58
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD	+86-15350851019 +86-15383190639	admin@86-ss.com	China	1000	58
Dorne Chemical Technology co. LTD	+86-86-13583358881 +8618560316533	Ethan@dornechem.com	China	3128	58
Hebei Yime New Material Technology Co., Ltd.	+86-66697723 +86-17703311139	admin@china-yime.com	China	563	58
Shanghai Yunao International Trade Co., Ltd	+8617621705551	asdf@shanghaihg.cn	China	265	58
qingdao future trading Co., Ltd	+86-13335044410 +86-13335044410	cui56813@163.com	China	110	58

D-아르기닐-2,6-디메틸-L-티로실-L-리실-L-페닐알라닌미드 관련 검색:

Hexapeptide-11 L-Cysteine, L-cysteinylglycyl-L-glutaminyl-L-arginyl-L-α-glutamyl-L-threonyl-L-prolyl-L-α-glutamylglycyl-L-alanyl-L-α-glutamyl-L-alanyl-L-lysyl-L-prolyl-L-tryptophyl-L-tyrosyl-, cyclic (1→17)-disulfide DERMASEPTIN PHYLLOMEDUSA SAUVAGII Vantas Eptifibatide Acetate DSIP Ipamorelin 2'-Deoxyadenosine Bithionol Octamethylcyclotetrasiloxane