PF-06700841 tosylate
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PF-06700841 tosylate 속성
- 끓는 점
- 637.1±65.0 °C(Predicted)
- 밀도
- 1.63±0.1 g/cm3(Predicted)
- 저장 조건
- room temp
- 용해도
- DMSO: 78 mg/mL (200.31 mM);Ethanol: 78 mg/mL (200.31 mM)
- 물리적 상태
- 가루
- 산도 계수 (pKa)
- 7.28±0.10(Predicted)
- 색상
- 흰색에서 베이지색
- 수용성
- Water: Insoluble
안전
PF-06700841 tosylate C화학적 특성, 용도, 생산
Characteristics
Class: non-receptor tyrosine kinaseTreatment: immunological disorders
Other name: PF-06700841; Brepocitinib
Elimination half-life = 3.8–7.5 h
Protein binding = 39%
용도
PF-06700841 tosylate salt has been used as an inhibitor of Janus kinase1 (JAK1) to study its therapeutic effect on the adjuvant induced arthritis (AIA) rat model. It has also been used as an inhibitor of interferon-α/β receptor alpha chain (IFNAR1) signaling adaptor tyrosine kinase (2TYK2) in mice.Biochem/physiol Actions
PF-06700841 prevents IL-23 (interleukin 23) signaling through TYK2 (Tyrosine-protein kinase 2)/JAK1 (Janus kinase 1) inhibition.PF-06700841 tosylate 준비 용품 및 원자재
원자재
준비 용품
PF-06700841 tosylate 공급 업체
글로벌( 66)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32760 | 60 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 |
figo.gao@foxmail.com | China | 7287 | 58 |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 |
contact@trustwe.com | China | 5738 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 |
laboratory@coreychem.com | China | 30253 | 58 |
| NINGBOBENKANGJS PHARMTECHCO., LTD | +8615990591583 15990591583 |
CHINA | 2029 | 58 | |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 |
sales@hzclap.com | CHINA | 6313 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 |
sales@sarms4muscle.com | China | 10522 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 |
sales@invivochem.cn | United States | 6393 | 58 |
| LEAP CHEM CO., LTD. | +86-852-30606658 |
market18@leapchem.com | China | 24738 | 58 |
| Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 |
sales@chemhifuture.com | China | 3136 | 58 |
PF-06700841 tosylate 관련 검색:
PF-6274484
PF-9366
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PF-06700841-TsOH
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PF-06650833
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PF-01247324
PNU 100480
PF 05175157
Ketohexokinase inhibitor 1
PF-562271