K-252A
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K-252A 속성
- 녹는점
- 262-273℃ (decomposition) (methanol )
- 끓는 점
- 685.3±55.0 °C(Predicted)
- 밀도
- 1.68
- 인화점
- 87℃
- 저장 조건
- -20°C
- 용해도
- DMF: 1mg/mL
- 산도 계수 (pKa)
- 11.95±0.40(Predicted)
- 물리적 상태
- 동결건조된 고체.
- 색상
- 흰색 또는 황백색
- 안정성
- 제공된 대로 구매일로부터 1년 동안 안정적입니다. DMSO의 솔루션은 -20°에서 최대 3개월 동안 보관할 수 있습니다.
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | Xi,T | ||
---|---|---|---|
위험 카페고리 넘버 | 61-20/21/22-68/20/21/22 | ||
안전지침서 | 22-24/25-45-36/37-53 | ||
유엔번호(UN No.) | NA 1993 / PGIII | ||
WGK 독일 | 3 | ||
RTECS 번호 | NZ0550000 | ||
F 고인화성물질 | 8-10 | ||
HS 번호 | 29349990 |
K-252A C화학적 특성, 용도, 생산
개요
K252a is a staurosporine analog isolated from Nocardiopsis sp. soil fungi that inhibits protein kinase (PK) C, PKA, Ca2+/calmodulin-용도
K-252a is used to inhibit protein kinases involved in cell signaling processes, including CaM kinase; phosphorylase kinase, serine/threonine kinases, Trk. It is used to inhibit the actions of nerve growth factor (NGF) on PC1 2 cells and to inhibit smooth muscle myosin light chain kinase .정의
ChEBI: A organic heterooctacyclic compound that is a potent inhibitor of protein kinase C and is isolated from Nocardiopsis sp K-252a생물학적 활성
Non-selective protein kinase inhibitor; analog of staurosporine. Inhibits PKC (IC 50 = 32.9 nM), Ca 2+ /calmodulin-stimulated phosphodiesterases (IC 50 = 1.3-2.9 μ M), MLCK (K i = 20 nM) and receptor tyrosine kinases. Inhibits the oncogenic properties of MET; prevents autophosphorylation and activation of downstream effectors (MAPK, Akt).K-252A 준비 용품 및 원자재
원자재
준비 용품
K-252A 공급 업체
글로벌( 146)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
BOC Sciences | +1-631-485-4226 |
inquiry@bocsci.com | United States | 19553 | 58 |
TopScience Biochemical | 00852-68527855 |
info@itopbiochem.com | China Hong Kong | 902 | 58 |
Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 |
contact@fuxinpharm.com | China | 10297 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
Alfa Chemistry | +1-5166625404 |
Info@alfa-chemistry.com | United States | 21317 | 58 |
Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 |
masar@topule.com | China | 8474 | 58 |
Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 |
info@chemextension.com | China | 42057 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 |
sales@aladdinsci.com | United States | 57511 | 58 |
3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 |
3bsc@sina.com | China | 15848 | 69 |
Chemsky (shanghai) International Co.,Ltd | 021-50135380 |
shchemsky@sina.com | China | 15421 | 60 |
K-252A 관련 검색:
설파마이드 질산칼륨
PROTEIN KINASE INHIBITOR KT 5823
1,3,5,7,9-Pentaoxa-252, 452,652,852-tetraplumbacyclotridec-11 -ene-10,13-dione, (Z)-
Amberlite 252, Ion Exchange Resin
HC-252
AKOS 213-252
PROTEIN KINASE INHIBITOR KT 5720
C.I. Acid Red 252
CAMP-DEPENDENT PROTEIN KINASE INHIBITOR,PROTEIN KINASE INHIBITOR, CAMP-DEPENDENT
GP120 (252-272) (1)
CAMP-DEPENDENT PROTEIN KINASE INHIBITOR (14-24) AMIDE
AMBERLITE(R) 252,AMBERLITE(R) 252C
protein kinase inhibitor KT 5926
protein kinase inhibitor peptide
protein kinase inhibitor peptide (6-24)
cGMP-Dependent Protein Kinase Inhibitor Peptide
7-CHLORO-3-(CYCLOPROPYLCARBONYL)-4-HYDROXY-2(1H)-QUINOLINE[L-701, 252]