(R)-3-HYDROXYMETHYL-PIPERAZINE-1-CARBOXYLICACIDTERT-부틸에스테르
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(R)-3-HYDROXYMETHYL-PIPERAZINE-1-CARBOXYLICACIDTERT-부틸에스테르 속성
- 녹는점
- 68-70°C
- 끓는 점
- 322.9±22.0 °C(Predicted)
- 밀도
- 1.085±0.06 g/cm3(Predicted)
- 저장 조건
- Keep in dark place,Sealed in dry,Room Temperature
- 용해도
- 클로로포름(약간 용해됨), 메탄올(약간 용해됨)
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 산도 계수 (pKa)
- 14.97±0.10(Predicted)
- 색상
- 흰색에서 황백색까지
- InChI
- InChI=1S/C10H20N2O3/c1-10(2,3)15-9(14)12-5-4-11-8(6-12)7-13/h8,11,13H,4-7H2,1-3H3/t8-/m1/s1
- InChIKey
- NSILYQWHARROMG-MRVPVSSYSA-N
- SMILES
- N1(C(OC(C)(C)C)=O)CCN[C@@H](CO)C1
- CAS 데이터베이스
- 278788-66-2(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
그림문자(GHS): |
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신호 어: | Danger | ||||||||||||||||||||||||
유해·위험 문구: |
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예방조치문구: |
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(R)-3-HYDROXYMETHYL-PIPERAZINE-1-CARBOXYLICACIDTERT-부틸에스테르 C화학적 특성, 용도, 생산
Synthesis
1,4-bis-Boc-2-hydroxymethylpiperazine (13.9 kg) and 95% ethanol (30 kg) were added to the reactor, followed by the addition of an aqueous solution (water 21 kg) of configured sodium hydroxide (3.5 kg). The reaction mixture was then heated to reflux. Once the reaction was completed, ethanol was concentrated under reduced pressure. Subsequently, 30 kg of dichloromethane was added and the mixture was separated into liquid and aqueous phases. The aqueous phase was extracted three times with 3 × 20 kg of dichloromethane, and the organic phases were combined. The resulting solution was washed once with 40 kg of a 15% aqueous sodium chloride solution and dried with anhydrous sodium sulfate. Further purification was carried out to obtain (R)-1-BOC-3-(Hydroxymethyl)piperazine.![(R)-1-BOC-3-(Hydroxymethyl)piperazine (R)-1-BOC-3-(Hydroxymethyl)piperazine](/NewsImg/2023-10-19/6383330827112240526698564.jpg)
(R)-3-HYDROXYMETHYL-PIPERAZINE-1-CARBOXYLICACIDTERT-부틸에스테르 준비 용품 및 원자재
원자재
3H-Oxazolo[3,4-a]pyrazine-7(1H)-carboxylic acid, tetrahydro-1,3-dioxo-, 1,1-dimethylethyl ester, (8aR)-
(R)-1,4-(DI-BOC)-2-(HYDROXYMETHYL)PIPERAZINE
준비 용품
(R)-3-HYDROXYMETHYL-PIPERAZINE-1-CARBOXYLICACIDTERT-부틸에스테르 공급 업체
글로벌( 236)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
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Shanghai Boc Chemical Co., Ltd. | 021-34975602; +8618721111801 |
shangli@bocchem.com | China | 138 | 58 |
Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 |
Mandy@hangyubiotech.com | China | 10988 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29798 | 60 |
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9332 | 55 |
career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29892 | 58 |
Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 |
figo.gao@foxmail.com | China | 7621 | 58 |
Accela ChemBio Inc. | +1-858-6993322 |
info@accelachem.com | United States | 19372 | 58 |
Chengdu Feibo Pharm Technology Co., Ltd | 15982321820 |
abby@arkpharm.com | CHINA | 3279 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 |
sales@chemdad.com | China | 39916 | 58 |
Alchem Pharmtech,Inc. | 8485655694 |
sales@alchempharmtech.com | United States | 63711 | 58 |
(R)-3-HYDROXYMETHYL-PIPERAZINE-1-CARBOXYLICACIDTERT-부틸에스테르 관련 검색:
N-BOC-(3S,4S)-3,4-PYRROLIDINEDIOL
(S)-4-N-Boc-piperazine-2-carboxylic acid methyl ester
(R)-N-Boc-piperazine-2-carboxylic acid methyl ester
(S)-1-Boc-3-hydroxymethyl-piperazine
exo-3-Boc-3-azabicyclo[3.1.0]hexane-6-methanol
3-N-Boc-Cis-Tetrahydrofuran-3,4-Diamine
tert-butyl (3S)-3-(hydroxymethyl)-2-azabicyclo[3.1.0]hexane-2-carboxylate
(6R,7S)-2-BOC-2-AZA-BICYCLO[2.2.1]HEPT-5-EN-3-ONE
(2S,4R)-4-hydroxy-2-methyl-pyrrolidine-1-carboxylic acid tert-butyl ester
rel-(3r,4r)-3-(boc-amino)-5-fluoropiperidine
tert-butyl ((3R,4R)-4-hydroxytetrahydro-2H-pyran-3-yl)carbamate
tert-butyl (3R,4S)-3-amino-4-methylpyrrolidine-1-carboxylate
tert-butyl (3R)-3-aMino-4-(hydroxyMethyl)pyrrolidine-1-carboxyla
(R)-tert-butyl 4-(1-aminoethyl)piperidine-1-carboxylate
1-Pyrrolidinecarboxylicacid,3-(methylamino)-,1,1-dimethylethylester,(R)-(9CI)
(R)-N-Boc-3-(aminomethyl)pyrrolidine
(R)-1-Boc-3-(Cyanomethyl)Piperidine
tert-butyl (2R,3S)-2-(3-aminopropyl)-3-((tert-butyldimethylsilyl)oxy)piperidine-1-carboxylate