BEPOTASTINE BESILATE
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BEPOTASTINE BESILATE 속성
- 녹는점
- 161-163°
- 알파
- D20 +6.0° (c = 5 in methanol)
- 저장 조건
- Inert atmosphere,Room Temperature
- 용해도
- DMSO (Slightly, Heated), Methanol (Slightly, Heated)
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 색상
- 흰색~밝은 베이지
- 안정성
- 흡습성
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
BEPOTASTINE BESILATE C화학적 특성, 용도, 생산
개요
Betotastine was introduced in Japan for the treatment of allergic rhinitis. This structurally-related derivative of chlorpheniramine and ebastine is prepared by condensation of optically-resolved 4-[1-(4-chlorophenyl)-1-(2-pyridyl)-methoxy]piperidine with ethyl 4-bromobutyrate followed by ester hydrolysis. Betotastine is the seventh marketed non-sedating histamine H1 antagonist. Its very low sedative side effect is due to very poor penetration in the central nervous system. Besides its potent and long-acting activity in models of allergic rhinitis, betotastine was also shown to act as a PAF antagonist and inhibit LTD4 in tracheal smooth muscle and ileum, IL-5 production by human peripheral blood mononuclear cells as well as eosinophil infiltration in the airway and peripheral blood. As a consequence, it is currently being developed against other allergic and respiratory disorders.화학적 성질
Off-White to Light Beige Solid용도
Bepotastine is a non-sedating, selective antagonist of histamine 1 (H1) receptor with pIC50 of 5.7정의
ChEBI: An organosulfonate salt obtained by combining equimolar amounts of bepotastine and benzenesulfonic acid. A topical, selective and non-sedating histamine (H1) receptor antagonist used for treatment of itching associated with allergic co junctivitis.BEPOTASTINE BESILATE 준비 용품 및 원자재
원자재
포스폰산,(3-메틸-2-옥소-5-헵티닐)-,디메틸에스테르
염화 티오닐
BENZOFURANCARBOXYLIC ACID
중탄산나트륨(중조)
수소화 리튬알미늄
메틸산 나트륨
세륨(III) 클로라이드 헵타하이드레이트
p-토루엔 술폰산 일수화물
준비 용품
BEPOTASTINE BESILATE 공급 업체
글로벌( 280)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Wuhan Fortuna Chemical Co., Ltd | +86-027-59207850 |
info@fortunachem.com | China | 5976 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 |
sales1@chuanghaibio.com | China | 5889 | 58 |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 +86-17331933971 |
deasea125996@gmail.com | China | 2472 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 |
sales@capot.com | China | 29791 | 60 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 |
sales01@cooperate-pharm.com | CHINA | 1803 | 55 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21634 | 55 |
| Hangzhou FandaChem Co.,Ltd. | +8615858145714 |
FandaChem@Gmail.com | China | 9174 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 |
product@chemlin.com.cn | CHINA | 3009 | 60 |
| Nanjing Finetech Chemical Co., Ltd. | 025-85710122 17714198479 |
sales@fine-chemtech.com | CHINA | 885 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29880 | 58 |
BEPOTASTINE BESILATE 관련 검색:
sodium phenyl sulfate
Isopropyl Benzenesulfonate
Butyl Benzenesulfonate
2-hydroxyethyl benzenesulfonate
Methyl benzenesulfonate
Ramelteon
2-[(S)-(4-Chlorophenyl)(4-piperidinyloxy)methyl]pyridine (2R,3R)-2,3-Dihydroxybutanedioate
4-[(4-Chlorophenyl)-2-pyridinylmethoxy]-1-piperidinebutanoic acid
Bepotastine Ethyl Ester
1-Piperidinebutanoic acid, 4-[(4-chlorophenyl)-2-pyridinylmethoxy]-, (R)-
Fasudil hydrochloride
FMOC-GLY-GLY-GLY-OH
5-alpha-Hydroxy- Laxogenin
5-[Bis(2-hydroxyethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic acid ethyl ester
1-Methyl-5-amino-1H-benzimidazole-2-butanoic acid ethyl ester
ethyl 4-(1-methyl-5-nitro-1H-benzo[d]imidazol-2-yl)butanoate
Benzenesulfonamide
Ethyl benzenesulphonate