클로르테녹사진
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클로르테녹사진 속성
- 녹는점
- 146-147° (dec)
- 끓는 점
- 303°C (rough estimate)
- 밀도
- 1.2414 (rough estimate)
- 굴절률
- 1.5500 (estimate)
- 저장 조건
- Store at -20°C
- 용해도
- DMSO에 용해됨
- 산도 계수 (pKa)
- 12.70±0.40(Predicted)
안전
클로르테녹사진 C화학적 특성, 용도, 생산
Originator
Reugaril ,Farber ,Italy ,1966Manufacturing Process
A mixture of 4 liters chloroform and 1,050 cc ethanol was saturated with dry hydrogen chloride gas at -5°C to +5°C in a vessel having a net volume of 15 liters and provided with a stirring device, reflux cooler, gas feed line, thermometer and dropping funnel. 455 g acrolein which had been precooled to 0°C were added dropwise to the solution over a period of 1 to 2 hours while maintaining the temperature below +5°C and vigorously stirring. 1,070 g salicylamide and 1,080 g glacial acetic acid were added to the resulting solution of beta-chloropropionaldehyde acetal, thereby forming a suspension which was heated to 60°C while stirring. A clear solution was formed which was maintained at 60°C for an additional hour. The solution was allowed to cool to about 40°C and was then washed with water by passing a strong stream of water under the surface of the chloroform and continuously withdrawing the upper phase. When the water had reached a pH of 3-4, the precipitated reaction product was separated by vacuum filtration. The chloroform phase of the filtrate was evaporated under a weak vacuum and the residue was combined with the precipitate first obtained. The combined products were stirred with 2 liters of a 5% sodium hydroxide solution. The raw reaction product was then washed with water, dried and recrystallized from ethanol. The product had the melting point of 146°C to 147°C (decomposition). The yield was 1,260 g, corresponding to 76% of the theoretical yield.Therapeutic Function
Antipyretic, Analgesic클로르테녹사진 준비 용품 및 원자재
원자재
준비 용품
클로르테녹사진 공급 업체
글로벌( 14)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
Career Henan Chemica Co | +86-0371-86658258 +8613203830695 |
laboratory@coreychem.com | China | 30250 | 58 |
Aikon International Limited | 025-66113011 18112977050 |
cb6@aikonchem.com | China | 15495 | 58 |
Suzhou Rovathin Foreign Trade Co.,Ltd | 0512-65816829 18662214788 |
info@rovathin.com.cn | China | 9544 | 58 |
Amel Pharmatech Corporation | 888-4366503 |
sales@amelpharmatech.com | China | 4128 | 58 |
Changzhou Chenhong Biotechnology Co., Ltd. | 0519-85788828 13775037613 |
sales@chemrenpharm.com | China | 3600 | 58 |
Shanghai Hecheng Medical Technology Co., LTD | 13564747822 |
669027880@qq.com | China | 943 | 58 |
Changzhou Furuisi Biotechnology Co., Ltd | 0519-85524369 |
3477467573@qq.com | China | 8618 | 58 |
Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223; |
psaitong@jm-bio.com | China | 29778 | 58 |
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd | 15229059051 |
1027@dideu.com | China | 9975 | 58 |
클로르테녹사진 관련 검색:
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