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metomidate

metomidate 구조식 이미지

카스 번호:: 5377-20-8

상품명:: metomidate

동의어(영문):: EM-01;Hypnodil;AquacalM;MethoxyMol;metomidate;Methomidate;MethoxyMol R-7315;Etomidate impurity B CRS;Etomidate Impurity 2 (Etomidate EP Impurity B);Methyl 3-(1-phenylethyl)imidazole-5-carboxylate

CBNumber:: CB9913785

분자식:: C13H14N2O2

포뮬러 무게:: 230.26

MOL 파일:: 5377-20-8.mol

속성

안전

용도

metomidate 속성

끓는 점: 372.26°C (rough estimate)

밀도: 1.13

굴절률: 1.6450 (estimate)

저장 조건: Refrigerator

용해도: 클로로포름, 메탄올에 용해됨

산도 계수 (pKa): 4.15±0.23(Predicted)

색상: 무색~담황색

InChI: InChI=1S/C13H14N2O2/c1-10(11-6-4-3-5-7-11)15-9-14-8-12(15)13(16)17-2/h3-10H,1-2H3

InChIKey: FHFZEKYDSVTYLL-UHFFFAOYSA-N

SMILES: C1N(C(C2=CC=CC=C2)C)C(C(OC)=O)=CN=1

안전

metomidate C화학적 특성, 용도, 생산

화학적 성질

Colourless Hazy Oil

용도

Metomidate is a the methyl ester analogue of Etomidate (E933300), with sedative and hypnotic properties. Metomidate is mainly used as an anesthetic for veterinary use on its own or in combination with Azaperone (A802200) and other sedatives.

Mechanism of action

Metomidate reduces plasma cortisol and glucose concentrations and increases fish pigmentation, presumably because of increased production of melanocyte-stimulating hormone on the same primary protein as adrenocorticotropic hormone (ACTH). Imidazole anesthetics (e.g., metomidate and etomidate) interrupt cortisol synthesis in mammals by suppressing the enzyme 11-beta-hydroxylase, which is necessary for cortisol production.

metomidate 준비 용품 및 원자재

원자재

준비 용품

metomidate 관련 검색:

(R)-(+)-1-(1-PHENYLETHYL)-1H-IMIDAZOLE-5-CARBOXYLIC ACID (S)-1-(1-phenylethyl)-1H-imidazole-5-carboxylic acid Formamide, N-[(1R)-1-phenylethyl]- S-(-)-EtoMidate Formamide, N-formyl-N-(1-phenylethyl)- 1H-Imidazole-5-carboxylic acid, 1-[(1R)-1-phenylethyl]-, 2,3-dihydroxypropyl ester Etomidate Impurity 1 Etomidate Impurity 7 ethyl (R)-2,3-dihydro-3-(1-phenylethyl)-2-thioxo-1H-imidazole-4-carboxylate methyl (R)-1-(1-phenylethyl)-1H-imidazole-5-carboxylate Dexmedetomidine Etomidate Ethonam propoxate metomidate Metomidate Hydrochloride (+)-METOMIDATE HYDROCHLORIDE Ethonam nitrate