ChemicalBook >제품 카탈로그 >아미솜트라딘

아미솜트라딘

아미솜트라딘 구조식 이미지

카스 번호:: 550-28-7

한글명:: 아미솜트라딘

동의어(한글):: 아미솜트라딘

상품명:: amisometradine

동의어(영문):: Rolicton;amisometradine;Aminoisometradin;Aminoisometradine;6-Amino-3-methyl-1-(2-methylallyl)uracil;6-amino-3-methyl-1-(2-methylallyl)pyrimidine-2,4-quinone;6-amino-3-methyl-1-(2-methylprop-2-enyl)pyrimidine-2,4-dione;6-azanyl-3-methyl-1-(2-methylprop-2-enyl)pyrimidine-2,4-dione;6-Amino-3-methyl-1-(2-methyl-2-propenyl)pyrimidine-2,4(1H,3H)-dione;2,4(1H,3H)-Pyrimidinedione, 6-amino-3-methyl-1-(2-methyl-2-propen-1-yl)-

CBNumber:: CB9920813

분자식:: C9H13N3O2

포뮬러 무게:: 195.22

MOL 파일:: 550-28-7.mol

속성

안전

용도

공급 업체 10

아미솜트라딘 속성

녹는점: 175°

끓는 점: 331.89°C (rough estimate)

밀도: 1.1985 (rough estimate)

굴절률: 1.5100 (estimate)

저장 조건: Amber Vial, -20°C Freezer, Under inert atmosphere

용해도: DMSO(약간 용해됨), 메탄올(약간 용해됨)

물리적 상태: 고체

물리적 상태: 단단한 모양

산도 계수 (pKa): 4.97±0.70(Predicted)

색상: 흰색에서 옅은 베이지까지

안정성: 감광성

안전

아미솜트라딘 C화학적 특성, 용도, 생산

Originator

Rolicton,Searle,US,1956

Manufacturing Process

Preparation of the ethyl analog is as follows (methyl isocyanate is used in amisometradine manufacture).
To a cooled and stirred solution of 142 parts of methallylamine in 900 parts of benzene, 156 parts of ethyl isocyanate are added dropwise. Upon concentration in vacuum N-ethyl-N'-methallylurea is obtained.
260 parts of this urea derivative are dissolved in 500 parts of acetic anhydride and treated with 157 parts of cyanoacetic acid at 60°C and heated at that temperature for 2 hours. The solution is then concentrated in vacuum to a syrup. 100 parts of water are added and the vacuum distillation is repeated. The remaining syrup contains a mixture of N-cyanoacetyl-N-ethyl-N'- methallylurea and a small quantity of N-cyanoacetyl-N-methallyl-N'-ethylurea.
This syrup is treated with sufficient 20% sodium hydroxide solution to raise the pH to 10. A violent reaction occurs. The reaction mixture is diluted with 50 parts of water, stirred, cooled and filtered. The material collected on the filter is recrystallized from 10% ethanol to yield a mixture of 1-methallyl-3-ethyl-6- amino-1,2,3,4-tetrahydro-2,4-pyrimidinedione and 1-ethyl-3-methallyl-6- amino-1,2,3,4-tetrahydro-2,4-pyrimidinedione melting at about 157-159°C.

Therapeutic Function

Diuretic

아미솜트라딘 준비 용품 및 원자재

원자재

시안초산 메틸 이소시아네이트 2-메틸알릴아민

준비 용품

아미솜트라딘 공급 업체

글로벌( 10)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Shaanxi Didu New Materials Co. Ltd	+86-89586680 +86-13289823923	1026@dideu.com	China	9003	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
Energy Chemical	021-58432009 400-005-6266	marketing@energy-chemical.com	China	44941	58
Changzhou Furuisi Biotechnology Co., Ltd	0519-85524369	3477467573@qq.com	China	8618	58
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd	15229059051	1027@dideu.com	China	9968	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	23963	58
LGC Science (Shanghai) Ltd.	17717235263	cindy.yang@lgcgroup.com	China	11572	58

아미솜트라딘 관련 검색:

6-amino-1-propyluracil 1,3-DIALLYLUREA amisometradine 1-ALLYLPYRIMIDINE-2,4(1H,3H)-DIONE 6-AMINO-1-ETHYL-1H-PYRIMIDINE-2,4-DIONE