Cyclosporin H suppliers
Cyclosporin H
- CAS:
- 83602-39-5
- MF:
- C62H111N11O12
- MW:
- 1202.61
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Properties
- Melting point:
- 148-151°C
- Boiling point:
- 1293.8±65.0 °C(Predicted)
- Density
- 1.016±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- Chloroform (Slightly), Methanol (Slightly, Heated, Sonicated)
- pka
- 13.32±0.70(Predicted)
- form
- powder
- color
- white to beige
- optical activity
- [α]/D -100 to -115°, c = 0.5 in methanol
Safety Information
- Symbol(GHS)
GHS07,GHS08
- Signal word
- Danger
- Hazard statements
- H302-H350-H360
- Precautionary statements
- P202-P264-P270-P280-P301+P312-P308+P313
- HS Code
- 29420000
Use
Cyclosporin H is a minor analogue of the cyclosporin family which is immunologically inactive as it does not bind to immunophilin. Cyclosporin H is the most extensively investigated of the minor cyclosporin analogues . It is a potent inhibitor of tumor-promoting phorbol esters on mouse skin in vivo, and of calcium/calmodulin-dependent EF-2 phosphorylation in vitro, a potent and selective antagonist of formyl peptide receptor and inhibitor of formyl peptide-induced superoxide formation.
129 supplier list of "Cyclosporin H"
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