Mk-2461 . suppliers
Mk-2461 .
- CAS:
- 917879-39-1
- MF:
- C24H25N5O5S
- MW:
- 495.55
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Properties
- Melting point:
- 192-193 °C
- Boiling point:
- 732.4±70.0 °C(Predicted)
- Density
- 1.45±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- ≥24.8 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
- form
- solid
- pka
- 6.81±0.20(Predicted)
- color
- Light yellow to yellow
Safety Information
Use
MK-2461 is a novel ATP-competitive multitargeted kinase inhibitor that preferentially inhibits the activated c-Met receptor. MK-2461 is also a potent inhibitor of Ron, Flt1, Flt 3, PDGFRβ, and Mer receptors. Recent studies show that MK-2461 siginifciantly suppresses tumor growth of GTL-16 xenografts in mice and MK-2461 treatments effectively inhibit the growth of NIH3T3 tumors harboring c-Met single nucleotide mutants T3936C and T3997C.
48 supplier list of "Mk-2461 ."
![MK-2461](/images/pro-3.jpg)
- Product Name:MK-2461
- Products Intro:Brand:ChemShuttle
- Company Type: Trader
- Country/Region: UNITED STATES
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