ROSCOVITINE manufacturers and suppliers

Roscovitine suppliers

Properties

Melting point:: 106～107℃

Boiling point:: 577.5±60.0 °C(Predicted)

Density: 1.3

storage temp.: -20°C

solubility: Soluble in DMSO (up to 10 mg/ml, with warming) or in Ethanol (up to 10 mg/ml).

pka: 14.56±0.10(Predicted)

form: White to off-white solid

color: White

Stability:: Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.

InChIKey: BTIHMVBBUGXLCJ-OAHLLOKOSA-N

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H302+H312+H332-H315-H319

Precautionary statements: P501-P261-P270-P271-P264-P280-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330-P302+P352+P312-P304+P340+P312

Safety Statements: 22-24/25

WGK Germany: 3

HS Code: 29335990

Use

Roscovitine is a potent and selective inhibitor of cyclin-dependent kinases (CDKs). Roscovitine has been found to produce apoptosis in treated cancerous cells of non-small cell lung cancer (NSCLC) and other cancers. Studies show that Roscovitine displays increased anti-mitotic activity at the G1/S and G2/M phases of the cell cycle. Roscovitine maybe useful in the treatment of non-small cell lung c ancer (NSCLC), leukemia, HIV infection, herpes simplex infection, and the mechanisms of chronic inflammation disorders.

You can find Roscovitine suppliers, manufacturers, and distributors from countries such as China, United States and the United Kingdom here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.