SINEFUNGIN manufacturers and suppliers

SINEFUNGIN suppliers

Properties

alpha: D25 -2.61° (c = 5 in water); D23 +12 ±2° (c = 0.227 in water)

Boiling point:: 783.2±70.0 °C(Predicted)

Density: 1.91±0.1 g/cm3(Predicted)

storage temp.: 2-8°C

solubility: H₂O: soluble

form: powder

pka: pKa (66% DMF): 2.9, 3.9, 8.9, 10.2(at 25℃)

color: white to yellow

Stability:: Stable for 2 years from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 1 month.

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H302-H315-H319-H335

Precautionary statements: P261-P280-P301+P312-P302+P352-P305+P351+P338

Hazard Codes: Xn

Risk Statements: 22

Safety Statements: 36

WGK Germany: 3

RTECS: HE3140000

HS Code: 29419090

Toxicity: LD50 s.c. in mice: 185 mg/kg (Hamill, Hoehn, J. Antibiot.)

Use

Sinefungin, a polar nucleoside antifungal active with broad biological activity, was isolated from a number of species of Streptomyces in the early 1970s. Sinefungin acts by inhibiting a wide range of methyltransferases, including the methylation of bases in DNA and RNA which alters cytosine deamination and gene expression. Sinefungin is widely used as a bioprobe to block methyltransferase-dependent pathways.

You can find SINEFUNGIN suppliers, manufacturers, and distributors from countries such as China, United States and the United Kingdom here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.