Verteporfin suppliers
Verteporfin
- CAS:
- 129497-78-5
- MF:
- 2C41H42N4O8
- MW:
- 1437.61
Suppliers by country/region
Company Type
Properties
- storage temp.
- -20°C
- solubility
- DMSO: soluble2mg/mL, clear (warmed)
- form
- powder
- color
- Black
- Stability:
- Stable for 2 years from date of purchsae as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
- InChIKey
- YHNBVDZVUQFVLS-RDSGBMLISA-N
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H315-H319-H335
- Precautionary statements
- P280-P305+P351+P338
- WGK Germany
- 3
- HS Code
- 2933997500
Use
Verteporfin was introduced in Switzerland as a second-generation photosensitizer for photodynamic therapy of wet age-related macular degeneration in patients with subfoveal choroidal neovascularisation. It is constituted of a mixture of two regioisomers resulting from nonselective monohydrolysis of the methyl tetraester. Upon irradiation with a lowenergy nonheat-generating laser light of 689nm wavelength, both regioisomeric benzoporphyrins are responsible for the local generation of singlet oxygen leading to free radical damage of neovascular endothelial cells in subfoveal lesions of patients with agerelated macular degeneration. The lipophilic drug is injected i.v. as a liposomal formulation in order to favor its uptake by plasma lipoproteins and distribution to cells with a high expression of low density lipoprotein receptors such as tumor and neovascular endothelial cells. Verteporfin is also being developed for the treatment of other eye diseases, nonmelanoma skin cancer and psoriasis.
141 supplier list of "Verteporfin"
$1.00/ 1KG
- Product Name:Verteporfin
- Products Intro:Purity: 99% | Package: 1KG;1USD
- Company Type: Reagent
- Country/Region: CHINA
$1.10/ 1g
- Product Name:Verteporfin
- Products Intro:Purity: 99.0% min|Package: 1g;1.1USD
- Company Type: Trader
- Country/Region: CHINA