GGTI 298 trifluoroacetate salt hydrate
|
- $90 - $1095
- Product name: GGTI 298 trifluoroacetate salt hydrate
- CAS: 1217457-86-7
- MF: C29H34F3N3O5S
- MW: 593.66
- EINECS:
- MDL Number:MFCD06409252
- Synonyms:GGTI 298 trifluoroacetate salt hydrate;N-[[4-(2-(R)-Amino-3-mercaptopropyl)amino]-2-naphthylbenzoyl]leucine methyl ester trifluoroacetate salt hydrate;GGTI-298 TFA;GGTI298 Trifluoroacetate;WALKWJPZELDSKT-UFABNHQSSA-N;GGTI 298 TFA salt;GGTI 298 TFA SALT;GGTI 298 (TRIFLUOROACETATE SALT);(S)-Methyl 2-(4-(((R)-2-amino-3-mercaptopropyl)amino)-2-(naphthalen-1-yl)benzamido)-4-methylpentanoate 2,2,2-trifluoroacetate
14 prices
Selected condition：
Brand
- American Custom Chemicals Corporation
- Cayman Chemical
- ChemScene
- CSNpharm
- Sigma-Aldrich
- TRC
Package
- 250μg
- 500μg
- 1mg
- 5MG
- 10mg
- 25mg
- 50mg
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0004652
- Product descriptionGGTI-298 TRIFLUOROACETATE SALT HYDRATE 95.00%
- Packaging5MG
- Price$501.62
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number16176
- Product descriptionGGTI 298 (trifluoroacetate salt) ≥95%
- Packaging500μg
- Price$106
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16176
- Product descriptionGGTI 298 (trifluoroacetate salt) ≥95%
- Packaging1mg
- Price$184
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16176
- Product descriptionGGTI 298 (trifluoroacetate salt) ≥95%
- Packaging5mg
- Price$816
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-7690
- Product descriptionGGTI298Trifluoroacetate >98.0%
- Packaging1mg
- Price$90
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-7690
- Product descriptionGGTI298Trifluoroacetate >98.0%
- Packaging5mg
- Price$180
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-7690
- Product descriptionGGTI298Trifluoroacetate >98.0%
- Packaging10mg
- Price$280
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-7690
- Product descriptionGGTI298Trifluoroacetate >98.0%
- Packaging25mg
- Price$550
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-7690
- Product descriptionGGTI298Trifluoroacetate >98.0%
- Packaging50mg
- Price$750
- Updated2021-12-16
- Buy
- ManufacturerCSNpharm
- Product numberCSN19197
- Product descriptionGGTI298Trifluoroacetate
- Packaging10mg
- Price$238
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product numberG5169
- Product descriptionGGTI 298 trifluoroacetate salt hydrate ≥90% (HPLC), film
- Packaging250μg
- Price$118
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberG5169
- Product descriptionGGTI 298 trifluoroacetate salt hydrate ≥90% (HPLC), film
- Packaging1mg
- Price$440
- Updated2024-03-01
- Buy
- ManufacturerTRC
- Product numberG368880
- Product descriptionGGTI298(TrifluoroacetateSalt)
- Packaging1mg
- Price$150
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberG368880
- Product descriptionGGTI298(TrifluoroacetateSalt)
- Packaging10mg
- Price$1095
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| American Custom Chemicals Corporation | INB0004652 | GGTI-298 TRIFLUOROACETATE SALT HYDRATE 95.00% | 5MG | $501.62 | 2021-12-16 | Buy |
| Cayman Chemical | 16176 | GGTI 298 (trifluoroacetate salt) ≥95% | 500μg | $106 | 2024-03-01 | Buy |
| Cayman Chemical | 16176 | GGTI 298 (trifluoroacetate salt) ≥95% | 1mg | $184 | 2024-03-01 | Buy |
| Cayman Chemical | 16176 | GGTI 298 (trifluoroacetate salt) ≥95% | 5mg | $816 | 2024-03-01 | Buy |
| ChemScene | CS-7690 | GGTI298Trifluoroacetate >98.0% | 1mg | $90 | 2021-12-16 | Buy |
| ChemScene | CS-7690 | GGTI298Trifluoroacetate >98.0% | 5mg | $180 | 2021-12-16 | Buy |
| ChemScene | CS-7690 | GGTI298Trifluoroacetate >98.0% | 10mg | $280 | 2021-12-16 | Buy |
| ChemScene | CS-7690 | GGTI298Trifluoroacetate >98.0% | 25mg | $550 | 2021-12-16 | Buy |
| ChemScene | CS-7690 | GGTI298Trifluoroacetate >98.0% | 50mg | $750 | 2021-12-16 | Buy |
| CSNpharm | CSN19197 | GGTI298Trifluoroacetate | 10mg | $238 | 2021-12-16 | Buy |
| Sigma-Aldrich | G5169 | GGTI 298 trifluoroacetate salt hydrate ≥90% (HPLC), film | 250μg | $118 | 2024-03-01 | Buy |
| Sigma-Aldrich | G5169 | GGTI 298 trifluoroacetate salt hydrate ≥90% (HPLC), film | 1mg | $440 | 2024-03-01 | Buy |
| TRC | G368880 | GGTI298(TrifluoroacetateSalt) | 1mg | $150 | 2021-12-16 | Buy |
| TRC | G368880 | GGTI298(TrifluoroacetateSalt) | 10mg | $1095 | 2021-12-16 | Buy |
Properties
Melting point :99.5-100°C
storage temp. :-20°C
solubility :DMSO: >20mg/mL
form :film &_& lyophilized
color :colorless
storage temp. :-20°C
solubility :DMSO: >20mg/mL
form :film &_& lyophilized
color :colorless
Safety Information
| Symbol(GHS): |
|
||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | ||||||||||||||||||||||||||||
| Hazard statements: |
|
||||||||||||||||||||||||||||
| Precautionary statements: |
|
Description
Post-translational protein prenylation, a process catalyzed by three different enzymes, occurs at the C-terminal of a number of proteins involved in cell growth control and oncogenesis. One of these enzymes, geranylgeranyltransferase I (GGTase I) modifies cysteines of proteins with CAAX terminal sequences, preferring either leucine or isoleucine in the X-position. The Rho family of proteins are typically geranylgeranylated by GGTase I. GGTI 298 is a CAAX peptidomimetic that selectively inhibits GGTase I with little effect on other prenylation enzymes such as farnesyltransferase. It has been shown to arrest human tumor cells (IC50 = 10 μM for A549 cells) in G0/G1 and induce apoptosis by inhibiting proteasome activity and up-regulating the expression of the cyclin-dependent kinase inhibitor p21.More related product prices
SilverRelated product price
- Silver
$29-6300