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ChemicalBook >> CAS DataBase List >> Methanone, [4-(4'-Methoxy[1,1'-biphenyl]-4-yl)-1H-1,2,3-triazol-1-yl](2-phenyl-1-piperidinyl)-

Methanone, [4-(4'-Methoxy[1,1'-biphenyl]-4-yl)-1H-1,2,3-triazol-1-yl](2-phenyl-1-piperidinyl)-

Methanone, [4-(4'-Methoxy[1,1'-biphenyl]-4-yl)-1H-1,2,3-triazol-1-yl](2-phenyl-1-piperidinyl)- price.
8 prices
Selected condition:
Brand
  • AK Scientific
  • ApexBio Technology
  • Cayman Chemical
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • ManufacturerAK Scientific
  • Product number6711DK
  • Product descriptionMethanone,[4-(4'-Methoxy[1,1'-biphenyl]-4-yl)-1H-1,2,3-triazol-1-yl](2-phenyl-1-piperidinyl)-
  • Packaging5mg
  • Price$201
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3197
  • Product descriptionKT195
  • Packaging5mg
  • Price$104
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3197
  • Product descriptionKT195
  • Packaging10mg
  • Price$192
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3197
  • Product descriptionKT195
  • Packaging25mg
  • Price$435
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number14818
  • Product descriptionKT195 ≥98%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14818
  • Product descriptionKT195 ≥98%
  • Packaging5mg
  • Price$93
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14818
  • Product descriptionKT195 ≥98%
  • Packaging10mg
  • Price$169
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14818
  • Product descriptionKT195 ≥98%
  • Packaging25mg
  • Price$381
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 6711DK Methanone,[4-(4'-Methoxy[1,1'-biphenyl]-4-yl)-1H-1,2,3-triazol-1-yl](2-phenyl-1-piperidinyl)- 5mg $201 2021-12-16 Buy
ApexBio Technology C3197 KT195 5mg $104 2021-12-16 Buy
ApexBio Technology C3197 KT195 10mg $192 2021-12-16 Buy
ApexBio Technology C3197 KT195 25mg $435 2021-12-16 Buy
Cayman Chemical 14818 KT195 ≥98% 1mg $32 2024-03-01 Buy
Cayman Chemical 14818 KT195 ≥98% 5mg $93 2024-03-01 Buy
Cayman Chemical 14818 KT195 ≥98% 10mg $169 2024-03-01 Buy
Cayman Chemical 14818 KT195 ≥98% 25mg $381 2024-03-01 Buy

Properties

solubility :DMF: 5 mg/ml; DMSO: 10 mg/ml; DMSO:PBS(pH 7.2) (1:2): 0.25 mg/ml
form :A crystalline solid

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H413 May cause long lasting harmful effects to aquatic life Hazardous to the aquatic environment, long-term hazard Category 4
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P273 Avoid release to the environment.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

The serine hydrolase known as α/β-hydrolase domain-containing protein 6 (ABHD6) hydrolyzes 2-arachidonoyl glycerol (2-AG; ) to regulate its availability at cannabinoid receptors. KT195 is a selective inhibitor of ABHD6 (IC50 = 10 nM) with negligible activity against other serine hydrolases such as DAGLβ. While it can be used as a probe to study ABHD6, it also has use as a negative control for studies of DAGLβ. By inactivating ABHD6, KT195 has been shown to induce a significant accumulation of 2-AG in Neuro2a cells. KT195 is also reported to reduce IL-1β secretion from lipopolysaccharide-treated macrophages.