Neutrophil Elastase Inhibitor
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- $62 - $543
- Product name: Neutrophil Elastase Inhibitor
- CAS: 1448314-31-5
- MF: C16H11N3O
- MW: 261.28
- EINECS:
- MDL Number:
- Synonyms:Neutrophil Elastase Inhibitor;Neutrophil Elastase Inhibitor Exclusive;1-(3-methylbenzoyl)indazole-3-carbonitrile;1H-Indazole-3-carbonitrile, 1-(3-methylbenzoyl)-;Neutrophil elastase inhibitor 1
10 prices
Selected condition：
Brand
- AK Scientific
- ApexBio Technology
- Cayman Chemical
Package
- 5mg
- 10mg
- 25mg
- 50mg
- ManufacturerAK Scientific
- Product number9751DV
- Product description1-(3-Methylbenzoyl)-1H-indazole-3-carbonitrile
- Packaging10mg
- Price$225
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number9751DV
- Product description1-(3-Methylbenzoyl)-1H-indazole-3-carbonitrile
- Packaging25mg
- Price$398
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3252
- Product descriptionNeutrophilElastaseInhibitor
- Packaging5mg
- Price$68
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3252
- Product descriptionNeutrophilElastaseInhibitor
- Packaging10mg
- Price$129
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3252
- Product descriptionNeutrophilElastaseInhibitor
- Packaging25mg
- Price$307
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3252
- Product descriptionNeutrophilElastaseInhibitor
- Packaging50mg
- Price$543
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number14922
- Product descriptionNeutrophil Elastase Inhibitor ≥95%
- Packaging5mg
- Price$62
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14922
- Product descriptionNeutrophil Elastase Inhibitor ≥95%
- Packaging10mg
- Price$115
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14922
- Product descriptionNeutrophil Elastase Inhibitor ≥95%
- Packaging25mg
- Price$270
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14922
- Product descriptionNeutrophil Elastase Inhibitor ≥95%
- Packaging50mg
- Price$477
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 9751DV | 1-(3-Methylbenzoyl)-1H-indazole-3-carbonitrile | 10mg | $225 | 2021-12-16 | Buy |
| AK Scientific | 9751DV | 1-(3-Methylbenzoyl)-1H-indazole-3-carbonitrile | 25mg | $398 | 2021-12-16 | Buy |
| ApexBio Technology | C3252 | NeutrophilElastaseInhibitor | 5mg | $68 | 2021-12-16 | Buy |
| ApexBio Technology | C3252 | NeutrophilElastaseInhibitor | 10mg | $129 | 2021-12-16 | Buy |
| ApexBio Technology | C3252 | NeutrophilElastaseInhibitor | 25mg | $307 | 2021-12-16 | Buy |
| ApexBio Technology | C3252 | NeutrophilElastaseInhibitor | 50mg | $543 | 2021-12-16 | Buy |
| Cayman Chemical | 14922 | Neutrophil Elastase Inhibitor ≥95% | 5mg | $62 | 2024-03-01 | Buy |
| Cayman Chemical | 14922 | Neutrophil Elastase Inhibitor ≥95% | 10mg | $115 | 2024-03-01 | Buy |
| Cayman Chemical | 14922 | Neutrophil Elastase Inhibitor ≥95% | 25mg | $270 | 2024-03-01 | Buy |
| Cayman Chemical | 14922 | Neutrophil Elastase Inhibitor ≥95% | 50mg | $477 | 2024-03-01 | Buy |
Properties
storage temp. :Store at -20°C
solubility :≤0.5mg/ml in ethanol;10mg/ml in DMSO;30mg/ml in dimethyl formamide
form :crystalline solid
solubility :≤0.5mg/ml in ethanol;10mg/ml in DMSO;30mg/ml in dimethyl formamide
form :crystalline solid
Safety Information
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Description
Neutrophil elastase is stored within cytoplasmic azurophilic granules in the neutrophil and released upon stimulation by pathogens where it acts either as free protein or is associated with neutrophil extracellular traps (NETs). Together with other proteases released from activated neutrophils, neutrophil elastase plays a critical role in degrading invading pathogens and thus provides the earliest line of defense in the immune system. Neutrophil elastase inhibitor is an N-benzoylindazole derivative that selectively targets the binding domain of neutrophil elastase (IC50 = 7 nM). It has been shown to inhibit additional serine proteases, thrombin and urokinase, only at higher, micromolar concentrations (IC50s = 1.9 and 6.6 μM, respectively).Suppliers and manufacturers
MQ (shanghai) Pharmaceuticals Co., Ltd.
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Shanghai Haohong Pharmaceutical Co., Ltd.
MedBioPharmaceutical Technology Inc
Aikon International Limited
Shaoguan Qicheng Biotechnology Co., Ltd
Nanjing Tengyi Biotechnology Co., Ltd
Shanghai Yifei Biotechnology Co. , Ltd.
ApexBio Technology