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ChemicalBook >> CAS DataBase List >> 2-Piperidinecarboxylic acid, 1-[[2,6-dimethoxy-4-[(2-methyl[1,1'-biphenyl]-3-yl)methoxy]phenyl]methyl]-, (2S)-

2-Piperidinecarboxylic acid, 1-[[2,6-dimethoxy-4-[(2-methyl[1,1'-biphenyl]-3-yl)methoxy]phenyl]methyl]-, (2S)-

2-Piperidinecarboxylic acid, 1-[[2,6-dimethoxy-4-[(2-methyl[1,1'-biphenyl]-3-yl)methoxy]phenyl]methyl]-, (2S)- price.
  • $28 - $1056
  • Product name: 2-Piperidinecarboxylic acid, 1-[[2,6-dimethoxy-4-[(2-methyl[1,1'-biphenyl]-3-yl)methoxy]phenyl]methyl]-, (2S)-
  • CAS: 1675201-83-8
  • MF: C29H33NO5
  • MW: 475.58
  • EINECS:-0
  • MDL Number:MFCD28978741
  • Synonyms:2-Piperidinecarboxylic acid, 1-[[2,6-dimethoxy-4-[(2-methyl[1,1'-biphenyl]-3-yl)methoxy]phenyl]methyl]-, (2S)-;PD1-PDL1 inhibitor 1;PD-1PD-L1 inhibitor;(2S)-1-[[2,6-Dimethoxy-4-[(2-methyl[1,1'-biphenyl]-3-yl)methoxy]phenyl]methyl]-2-piperidinecarboxylic acid;avelumab/PD-L1;T3655;(2S)-1-{2,6-Dimethoxy-4-[(2-methyl-3-biphenylyl)methoxy]benzyl}-2-piperidinecarboxylic acid;PD1-PDL1 inhibitor 1 (PD1-PDL1-IN1)
23 prices
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Brand
  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number9332EB
  • Product descriptionPD1-PDL1inhibitor1
  • Packaging10mg
  • Price$191
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA121482
  • Product description(S)-1-(2,6-Dimethoxy-4-((2-methyl-[1,1'-biphenyl]-3-yl)methoxy)benzyl)piperidine-2-carboxylicacid 98+%
  • Packaging1mg
  • Price$28
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA121482
  • Product description(S)-1-(2,6-Dimethoxy-4-((2-methyl-[1,1'-biphenyl]-3-yl)methoxy)benzyl)piperidine-2-carboxylicacid 98+%
  • Packaging5mg
  • Price$89
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA121482
  • Product description(S)-1-(2,6-Dimethoxy-4-((2-methyl-[1,1'-biphenyl]-3-yl)methoxy)benzyl)piperidine-2-carboxylicacid 98+%
  • Packaging10mg
  • Price$116
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA121482
  • Product description(S)-1-(2,6-Dimethoxy-4-((2-methyl-[1,1'-biphenyl]-3-yl)methoxy)benzyl)piperidine-2-carboxylicacid 98+%
  • Packaging25mg
  • Price$152
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA121482
  • Product description(S)-1-(2,6-Dimethoxy-4-((2-methyl-[1,1'-biphenyl]-3-yl)methoxy)benzyl)piperidine-2-carboxylicacid 98+%
  • Packaging50mg
  • Price$198
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA121482
  • Product description(S)-1-(2,6-Dimethoxy-4-((2-methyl-[1,1'-biphenyl]-3-yl)methoxy)benzyl)piperidine-2-carboxylicacid 98+%
  • Packaging100mg
  • Price$258
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA121482
  • Product description(S)-1-(2,6-Dimethoxy-4-((2-methyl-[1,1'-biphenyl]-3-yl)methoxy)benzyl)piperidine-2-carboxylicacid 98+%
  • Packaging250mg
  • Price$386
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA121482
  • Product description(S)-1-(2,6-Dimethoxy-4-((2-methyl-[1,1'-biphenyl]-3-yl)methoxy)benzyl)piperidine-2-carboxylicacid 98+%
  • Packaging1g
  • Price$965
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6172
  • Product descriptionPD-1/PD-L1inhibitor1
  • Packaging5mg
  • Price$103
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6172
  • Product descriptionPD-1/PD-L1inhibitor1
  • Packaging25mg
  • Price$348
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBP158531
  • Product descriptionPD1-PDL1 inhibitor 1
  • Packaging10mg
  • Price$105
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBP158531
  • Product descriptionPD1-PDL1 inhibitor 1
  • Packaging50mg
  • Price$367.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number19914
  • Product descriptionPD-1/PD-L1 Inhibitor 1 ≥98%
  • Packaging1mg
  • Price$36
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19914
  • Product descriptionPD-1/PD-L1 Inhibitor 1 ≥98%
  • Packaging5mg
  • Price$112
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19914
  • Product descriptionPD-1/PD-L1 Inhibitor 1 ≥98%
  • Packaging10mg
  • Price$207
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 9332EB PD1-PDL1inhibitor1 10mg $191 2021-12-16 Buy
Ambeed A121482 (S)-1-(2,6-Dimethoxy-4-((2-methyl-[1,1'-biphenyl]-3-yl)methoxy)benzyl)piperidine-2-carboxylicacid 98+% 1mg $28 2021-12-16 Buy
Ambeed A121482 (S)-1-(2,6-Dimethoxy-4-((2-methyl-[1,1'-biphenyl]-3-yl)methoxy)benzyl)piperidine-2-carboxylicacid 98+% 5mg $89 2021-12-16 Buy
Ambeed A121482 (S)-1-(2,6-Dimethoxy-4-((2-methyl-[1,1'-biphenyl]-3-yl)methoxy)benzyl)piperidine-2-carboxylicacid 98+% 10mg $116 2021-12-16 Buy
Ambeed A121482 (S)-1-(2,6-Dimethoxy-4-((2-methyl-[1,1'-biphenyl]-3-yl)methoxy)benzyl)piperidine-2-carboxylicacid 98+% 25mg $152 2021-12-16 Buy
Ambeed A121482 (S)-1-(2,6-Dimethoxy-4-((2-methyl-[1,1'-biphenyl]-3-yl)methoxy)benzyl)piperidine-2-carboxylicacid 98+% 50mg $198 2021-12-16 Buy
Ambeed A121482 (S)-1-(2,6-Dimethoxy-4-((2-methyl-[1,1'-biphenyl]-3-yl)methoxy)benzyl)piperidine-2-carboxylicacid 98+% 100mg $258 2021-12-16 Buy
Ambeed A121482 (S)-1-(2,6-Dimethoxy-4-((2-methyl-[1,1'-biphenyl]-3-yl)methoxy)benzyl)piperidine-2-carboxylicacid 98+% 250mg $386 2021-12-16 Buy
Ambeed A121482 (S)-1-(2,6-Dimethoxy-4-((2-methyl-[1,1'-biphenyl]-3-yl)methoxy)benzyl)piperidine-2-carboxylicacid 98+% 1g $965 2021-12-16 Buy
ApexBio Technology B6172 PD-1/PD-L1inhibitor1 5mg $103 2021-12-16 Buy
ApexBio Technology B6172 PD-1/PD-L1inhibitor1 25mg $348 2021-12-16 Buy
Biosynth Carbosynth BP158531 PD1-PDL1 inhibitor 1 10mg $105 2021-12-16 Buy
Biosynth Carbosynth BP158531 PD1-PDL1 inhibitor 1 50mg $367.5 2021-12-16 Buy
Cayman Chemical 19914 PD-1/PD-L1 Inhibitor 1 ≥98% 1mg $36 2024-03-01 Buy
Cayman Chemical 19914 PD-1/PD-L1 Inhibitor 1 ≥98% 5mg $112 2024-03-01 Buy
Cayman Chemical 19914 PD-1/PD-L1 Inhibitor 1 ≥98% 10mg $207 2024-03-01 Buy

Properties

Boiling point :630.2±55.0 °C(Predicted)
Density :1.182±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (up to at least 25 mg/ml) or in Ethanol (up to 20 mg/ml)
pka :2.34±0.20(Predicted)
form :solid
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

PD-1/PD-L1 Inhibitor 1 (1675201-83-8) inhibits (IC50 = <100nM) the formation of the PD-1/PD-L1 complex via binding to PD-L1 and inducing dimerization.1

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