Glycine, L-g-glutaMyl-S-(phenylMethyl)-L-cysteinyl-2-phenyl-,1,3-diethyl ester, (2R)-
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- $32 - $1600
- Product name: Glycine, L-g-glutaMyl-S-(phenylMethyl)-L-cysteinyl-2-phenyl-,1,3-diethyl ester, (2R)-
- CAS: 168682-53-9
- MF: C27H35N3O6S
- MW: 529.65
- EINECS:-0
- MDL Number:MFCD27982957
- Synonyms:(S)-ETHYL 2-AMINO-5-((R)-3-(BENZYLTHIO)-1-((R)-2-ETHOXY-2-OXO-1-PHENYLETHYLAMINO)-1-OXOPROPAN-2-YLAMINO)-5-OXOPENTANOATE;(2R)-L-gamma-Glutamyl-S-(phenylmethyl)-L-cysteinyl-2-phenylglycine 1,3-diethyl ester;Glycine, L-g-glutaMyl-S-(phenylMethyl)-L-cysteinyl-2-phenyl-,1,3-diethyl ester, (2R)-;Ezatiostat;Terrapin 199;Ezatiostat, >=98%;Ezatiostat, >96%;CS-1110
23 prices
Selected condition：
Brand
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- TRC
Package
- 1MG
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 1g
- ManufacturerAmbeed
- Product numberA178200
- Product descriptionEzatiostat 98+%
- Packaging5mg
- Price$69
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA178200
- Product descriptionEzatiostat 98+%
- Packaging10mg
- Price$116
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA178200
- Product descriptionEzatiostat 98+%
- Packaging50mg
- Price$302
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA178200
- Product descriptionEzatiostat 98+%
- Packaging100mg
- Price$392
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0008687
- Product descriptionEZATIOSTAT 95.00%
- Packaging5MG
- Price$503.46
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0008687
- Product descriptionEZATIOSTAT 95.00%
- Packaging1MG
- Price$135.45
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8225
- Product descriptionEzatiostat
- Packaging25mg
- Price$209
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number16248
- Product descriptionEzatiostat ≥98%
- Packaging25mg
- Price$442
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16248
- Product descriptionEzatiostat ≥98%
- Packaging10mg
- Price$199
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16248
- Product descriptionEzatiostat ≥98%
- Packaging5mg
- Price$109
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number16248
- Product descriptionEzatiostat ≥98%
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerChemenu
- Product numberCM295314
- Product description(S)-Ethyl2-amino-5-(((R)-3-(benzylthio)-1-(((R)-2-ethoxy-2-oxo-1-phenylethyl)amino)-1-oxopropan-2-yl)amino)-5-oxopentanoate 98%
- Packaging100mg
- Price$414
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-1713
- Product descriptionEzatiostat >96.0%
- Packaging5mg
- Price$96
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-1713
- Product descriptionEzatiostat >96.0%
- Packaging10mg
- Price$162
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-1713
- Product descriptionEzatiostat >96.0%
- Packaging50mg
- Price$480
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-1713
- Product descriptionEzatiostat >96.0%
- Packaging100mg
- Price$816
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Ambeed | A178200 | Ezatiostat 98+% | 5mg | $69 | 2021-12-16 | Buy |
| Ambeed | A178200 | Ezatiostat 98+% | 10mg | $116 | 2021-12-16 | Buy |
| Ambeed | A178200 | Ezatiostat 98+% | 50mg | $302 | 2021-12-16 | Buy |
| Ambeed | A178200 | Ezatiostat 98+% | 100mg | $392 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0008687 | EZATIOSTAT 95.00% | 5MG | $503.46 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0008687 | EZATIOSTAT 95.00% | 1MG | $135.45 | 2021-12-16 | Buy |
| ApexBio Technology | A8225 | Ezatiostat | 25mg | $209 | 2021-12-16 | Buy |
| Cayman Chemical | 16248 | Ezatiostat ≥98% | 25mg | $442 | 2024-03-01 | Buy |
| Cayman Chemical | 16248 | Ezatiostat ≥98% | 10mg | $199 | 2024-03-01 | Buy |
| Cayman Chemical | 16248 | Ezatiostat ≥98% | 5mg | $109 | 2024-03-01 | Buy |
| Cayman Chemical | 16248 | Ezatiostat ≥98% | 1mg | $32 | 2024-03-01 | Buy |
| Chemenu | CM295314 | (S)-Ethyl2-amino-5-(((R)-3-(benzylthio)-1-(((R)-2-ethoxy-2-oxo-1-phenylethyl)amino)-1-oxopropan-2-yl)amino)-5-oxopentanoate 98% | 100mg | $414 | 2021-12-16 | Buy |
| ChemScene | CS-1713 | Ezatiostat >96.0% | 5mg | $96 | 2021-12-16 | Buy |
| ChemScene | CS-1713 | Ezatiostat >96.0% | 10mg | $162 | 2021-12-16 | Buy |
| ChemScene | CS-1713 | Ezatiostat >96.0% | 50mg | $480 | 2021-12-16 | Buy |
| ChemScene | CS-1713 | Ezatiostat >96.0% | 100mg | $816 | 2021-12-16 | Buy |
Properties
Melting point :>94°C (dec.)
Boiling point :749.7±60.0 °C(Predicted)
Density :1.216±0.06 g/cm3(Predicted)
storage temp. :Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility :DMSO (Slightly), Methanol (Slightly)
pka :12?+-.0.46(Predicted)
form :Solid
color :White to Off-White
Boiling point :749.7±60.0 °C(Predicted)
Density :1.216±0.06 g/cm3(Predicted)
storage temp. :Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility :DMSO (Slightly), Methanol (Slightly)
pka :12?+-.0.46(Predicted)
form :Solid
color :White to Off-White
Safety Information
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Description
Glutathione S-transferases (GSTs) are ubiquitous multifunctional enzymes that play key roles in cellular detoxification and signal transduction by conjugating target substrates to glutathione. GSTP1-1, the most prevalent GST isozyme in nonhepatic tissues, binds to and inhibits the stress-activated c-Jun N-terminal kinase (JNK), an important regulator of cell proliferation, differentiation, and apoptosis. GSTP1-1 is overexpressed in many cancers and has been linked to drug resistance. Ezatiostat is a tripeptide analog of glutathione that can selectively inhibit GSTP1-1 catalytic activity (Ki = 400 nM) with minimal effect on the related GSTα and -μ families (Kis range from 20-75 μM). After intracellular de-esterification, the active form of ezatiostat, TLK117, binds to and inhibits GSTP1-1, restoring JNK-mediated cellular proliferation and differentiation signaling pathways. Ezatiostat has been shown to stimulate the proliferation of myeloid precursors in preclinical models and is under clinical examination for its potential prevention of myelosuppression in myelodysplastic syndrome.More related product prices
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$7.00 /1KG
Glycine, L-g-glutaMyl-S-(phenylMethyl)-L-cysteinyl-2-phenyl-,1,3-diethyl ester, (2R)- CAS: 168682-53-9
Glycine, L-g-glutaMyl-S-(phenylMethyl)-L-cysteinyl-2-phenyl-,1,3-diethyl ester, (2R)- CAS: 168682-53-9