17-AAG
- $28 - $8100
- Product name: 17-AAG
- CAS: 75747-14-7
- MF: C31H43N3O8
- MW: 585.69
- EINECS:
- MDL Number:MFCD04973892
- Synonyms:GELDANAMYCIN,17-DEMETHOXY-17-(2-PROPENYLAMINO)-;CP 127374;ALLYLAMINOGELDANAMYCIN;NSC-330507;17-(ALLYLAMINO)-17-DEMETHOXYGELDANAMYCIN;17-(ALLYLAMINO)-17-DESMETHOXYGELDANAMYCIN;17-(ALLYLAMINO)-17-DIMETHOXYGELDANAMYCIN;17-ALLYLAMINOGELDANAMYCIN
62 prices
Selected condition:
Brand
- Adipogen Life Sciences
- AHH
- AK Scientific
- Alfa Aesar
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Apolloscientific
- Arctom
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Iris Biotech GmbH
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 500μg
- 1
- 1unit
- 1mg
- 0.001g
- 5mg
- 10mg
- 20mg
- 25mg
- 50mg
- 100mg
- 200mg
- 250mg
- 1g
- 10mM(in 1mL DMSO)
- ManufacturerAdipogen Life Sciences
- Product numberBVT-0244-M005
- Product description17-AAG ≥98%(HPLC)
- Packaging5mg
- Price$75
- Updated2021-12-16
- Buy
- ManufacturerAHH
- Product numberMT-27757
- Product description17-Allylaminogeldanamycin 99%
- Packaging0.001g
- Price$230
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberX7553
- Product descriptionTanespimycin
- Packaging25mg
- Price$186
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberX7553
- Product descriptionTanespimycin
- Packaging200mg
- Price$462
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberJ66960
- Product description17-(Allylamino)-17-demethoxygeldanamycin, 99%
- Packaging200mg
- Price$362.65
- Updated2024-03-01
- Buy
- ManufacturerAlfa Aesar
- Product numberJ66960
- Product description17-(Allylamino)-17-demethoxygeldanamycin, 99%
- Packaging100mg
- Price$258.65
- Updated2024-03-01
- Buy
- ManufacturerAlfa Aesar
- Product numberJ66960
- Product description17-(Allylamino)-17-demethoxygeldanamycin, 99%
- Packaging25mg
- Price$109.65
- Updated2024-03-01
- Buy
- ManufacturerAmbeed
- Product numberA220462
- Product description(4E,6Z,8S,9S,10E,12S,13R,14S,16R)-19-(Allylamino)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-ylcarbamate 98+%
- Packaging5mg
- Price$95
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA220462
- Product description(4E,6Z,8S,9S,10E,12S,13R,14S,16R)-19-(Allylamino)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-ylcarbamate 98+%
- Packaging10mg
- Price$120
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA220462
- Product description(4E,6Z,8S,9S,10E,12S,13R,14S,16R)-19-(Allylamino)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-ylcarbamate 98+%
- Packaging25mg
- Price$240
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA220462
- Product description(4E,6Z,8S,9S,10E,12S,13R,14S,16R)-19-(Allylamino)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-ylcarbamate 98+%
- Packaging50mg
- Price$311
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA220462
- Product description(4E,6Z,8S,9S,10E,12S,13R,14S,16R)-19-(Allylamino)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-ylcarbamate 98+%
- Packaging100mg
- Price$404
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA220462
- Product description(4E,6Z,8S,9S,10E,12S,13R,14S,16R)-19-(Allylamino)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-ylcarbamate 98+%
- Packaging250mg
- Price$808
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA220462
- Product description(4E,6Z,8S,9S,10E,12S,13R,14S,16R)-19-(Allylamino)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-ylcarbamate 98+%
- Packaging1g
- Price$2503
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0009843
- Product description17-ALLYLAMINO-17-DEMETHOXYGELDANAMYCIN 95.00%
- Packaging250MG
- Price$868.56
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0009843
- Product description17-ALLYLAMINO-17-DEMETHOXYGELDANAMYCIN 95.00%
- Packaging50MG
- Price$752.14
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Adipogen Life Sciences | BVT-0244-M005 | 17-AAG ≥98%(HPLC) | 5mg | $75 | 2021-12-16 | Buy |
AHH | MT-27757 | 17-Allylaminogeldanamycin 99% | 0.001g | $230 | 2021-12-16 | Buy |
AK Scientific | X7553 | Tanespimycin | 25mg | $186 | 2021-12-16 | Buy |
AK Scientific | X7553 | Tanespimycin | 200mg | $462 | 2021-12-16 | Buy |
Alfa Aesar | J66960 | 17-(Allylamino)-17-demethoxygeldanamycin, 99% | 200mg | $362.65 | 2024-03-01 | Buy |
Alfa Aesar | J66960 | 17-(Allylamino)-17-demethoxygeldanamycin, 99% | 100mg | $258.65 | 2024-03-01 | Buy |
Alfa Aesar | J66960 | 17-(Allylamino)-17-demethoxygeldanamycin, 99% | 25mg | $109.65 | 2024-03-01 | Buy |
Ambeed | A220462 | (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-19-(Allylamino)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-ylcarbamate 98+% | 5mg | $95 | 2021-12-16 | Buy |
Ambeed | A220462 | (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-19-(Allylamino)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-ylcarbamate 98+% | 10mg | $120 | 2021-12-16 | Buy |
Ambeed | A220462 | (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-19-(Allylamino)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-ylcarbamate 98+% | 25mg | $240 | 2021-12-16 | Buy |
Ambeed | A220462 | (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-19-(Allylamino)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-ylcarbamate 98+% | 50mg | $311 | 2021-12-16 | Buy |
Ambeed | A220462 | (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-19-(Allylamino)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-ylcarbamate 98+% | 100mg | $404 | 2021-12-16 | Buy |
Ambeed | A220462 | (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-19-(Allylamino)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-ylcarbamate 98+% | 250mg | $808 | 2021-12-16 | Buy |
Ambeed | A220462 | (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-19-(Allylamino)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-ylcarbamate 98+% | 1g | $2503 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | INB0009843 | 17-ALLYLAMINO-17-DEMETHOXYGELDANAMYCIN 95.00% | 250MG | $868.56 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | INB0009843 | 17-ALLYLAMINO-17-DEMETHOXYGELDANAMYCIN 95.00% | 50MG | $752.14 | 2021-12-16 | Buy |
Properties
Melting point :201-203°C
Boiling point :797.8±60.0 °C(Predicted)
Density :1.21
RTECS :LX8932000
Flash point :>110°(230°F)
storage temp. :Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility :DMSO: soluble
form :solid
pka :8.62±0.70(Predicted)
color :Purple or dark red
Water Solubility :Soluble in DMSO at 150 mg/mL; soluble in ethanol at 5 mg/mL. Very poorly soluble in water
Sensitive :Light Sensitive
Stability :Stable for 1 year from date of purchase as supplied. Protect from moisture. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
InChIKey :AYUNIORJHRXIBJ-HTLBVUBBSA-N
SMILES :C12C(=O)C(=CC(=O)C=1NCC=C)NC(=O)C(C)=CC=C[C@H](OC)[C@@H](OC(=O)N)C(C)=C[C@H](C)[C@@H](O)[C@@H](OC)C[C@H](C)C2 |t:17,19,30|
CAS DataBase Reference :75747-14-7
Boiling point :797.8±60.0 °C(Predicted)
Density :1.21
RTECS :LX8932000
Flash point :>110°(230°F)
storage temp. :Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility :DMSO: soluble
form :solid
pka :8.62±0.70(Predicted)
color :Purple or dark red
Water Solubility :Soluble in DMSO at 150 mg/mL; soluble in ethanol at 5 mg/mL. Very poorly soluble in water
Sensitive :Light Sensitive
Stability :Stable for 1 year from date of purchase as supplied. Protect from moisture. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
InChIKey :AYUNIORJHRXIBJ-HTLBVUBBSA-N
SMILES :C12C(=O)C(=CC(=O)C=1NCC=C)NC(=O)C(C)=CC=C[C@H](OC)[C@@H](OC(=O)N)C(C)=C[C@H](C)[C@@H](O)[C@@H](OC)C[C@H](C)C2 |t:17,19,30|
CAS DataBase Reference :75747-14-7
Safety Information
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Signal word: | Warning | ||||||||||||||||||||||||||||
Hazard statements: |
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Precautionary statements: |
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Description
Geldanamycin is a potent inhibitor of Hsp90 that exhibits severe hepatotoxicity when used in vivo. 17-AAG is an analog of geldanamycin which has potent in vivo activity and reduced toxicity. Like other Hsp90 inhibitors, 17-AAG has diverse anti-tumor actions and has potential in treating certain types of cancer. 17-AAG inhibits the growth of prostate cancer cell lines (IC50 = 25-45 nM). 17-AAG promotes the degradation of HER2 and induces growth arrest and apoptosis in breast cancer cells overexpressing HER2 (IC50 = 4-72 nM).More related product prices
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