N,N'-[Sulfonylbis(1,4-phenylene)]bis(chloroacetamide)
![N,N'-[Sulfonylbis(1,4-phenylene)]bis(chloroacetamide) price.](/CAS/GIF/17328-16-4.gif)
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- $13 - $1200
- Product name: N,N'-[Sulfonylbis(1,4-phenylene)]bis(chloroacetamide)
- CAS: 17328-16-4
- MF: C16H14Cl2N2O4S
- MW: 401.26
- EINECS:
- MDL Number:MFCD00028183
- Synonyms:4',4'''-Sulfonylbis(α-chloroacetanilide);Bis[4-(chloroacetylamino)phenyl] sulfone;N,N'-[Sulfonylbis(1,4-phenylene)]bis(chloroacetamide);TC-E 5003;N,N'-(Sulfonyldi-4,1-phenylene)bis(2-chloroacetamide);N'-(Sulfonyldi-4;1-phenylene)bis(2-chloroacetamide);TC-E 5003 (NSC-30176)
23 prices
Selected condition：
Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- CSNpharm
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 003
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 50
- 100mg
- 250mg
- 500mg
- 002
- 5g
- 001
- ManufacturerAK Scientific
- Product number5881CA
- Product descriptionSulfone,bis((4-chloroacetylamino)phenyl)
- Packaging5g
- Price$802
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA169549
- Product descriptionTc-e5003 95+%
- Packaging1mg
- Price$13
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA169549
- Product descriptionTc-e5003 95+%
- Packaging5mg
- Price$28
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA169549
- Product descriptionTc-e5003 95+%
- Packaging10mg
- Price$42
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA169549
- Product descriptionTc-e5003 95+%
- Packaging25mg
- Price$71
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA169549
- Product descriptionTc-e5003 95+%
- Packaging50mg
- Price$106
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA169549
- Product descriptionTc-e5003 95+%
- Packaging100mg
- Price$160
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA169549
- Product descriptionTc-e5003 95+%
- Packaging250mg
- Price$272
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberHCH0121427
- Product description4',4''-SULFONYLBIS-(2-CHLOROACETANILIDE) 95.00%
- Packaging5MG
- Price$498.8
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7750
- Product descriptionTC-E5003
- Packaging50mg
- Price$71
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number17718
- Product descriptionTC-E 5003 ≥95%
- Packaging25mg
- Price$44
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17718
- Product descriptionTC-E 5003 ≥95%
- Packaging50mg
- Price$70
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17718
- Product descriptionTC-E 5003 ≥95%
- Packaging100mg
- Price$130
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17718
- Product descriptionTC-E 5003 ≥98%
- Packaging500mg
- Price$384
- Updated2024-03-01
- Buy
- ManufacturerCSNpharm
- Product numberCSN23150
- Product descriptionTC-E5003
- Packaging10mg
- Price$30
- Updated2021-12-16
- Buy
- ManufacturerCSNpharm
- Product numberCSN23150
- Product descriptionTC-E5003
- Packaging100mg
- Price$115
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 5881CA | Sulfone,bis((4-chloroacetylamino)phenyl) | 5g | $802 | 2021-12-16 | Buy |
| Ambeed | A169549 | Tc-e5003 95+% | 1mg | $13 | 2021-12-16 | Buy |
| Ambeed | A169549 | Tc-e5003 95+% | 5mg | $28 | 2021-12-16 | Buy |
| Ambeed | A169549 | Tc-e5003 95+% | 10mg | $42 | 2021-12-16 | Buy |
| Ambeed | A169549 | Tc-e5003 95+% | 25mg | $71 | 2021-12-16 | Buy |
| Ambeed | A169549 | Tc-e5003 95+% | 50mg | $106 | 2021-12-16 | Buy |
| Ambeed | A169549 | Tc-e5003 95+% | 100mg | $160 | 2021-12-16 | Buy |
| Ambeed | A169549 | Tc-e5003 95+% | 250mg | $272 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | HCH0121427 | 4',4''-SULFONYLBIS-(2-CHLOROACETANILIDE) 95.00% | 5MG | $498.8 | 2021-12-16 | Buy |
| ApexBio Technology | B7750 | TC-E5003 | 50mg | $71 | 2021-12-16 | Buy |
| Cayman Chemical | 17718 | TC-E 5003 ≥95% | 25mg | $44 | 2024-03-01 | Buy |
| Cayman Chemical | 17718 | TC-E 5003 ≥95% | 50mg | $70 | 2024-03-01 | Buy |
| Cayman Chemical | 17718 | TC-E 5003 ≥95% | 100mg | $130 | 2024-03-01 | Buy |
| Cayman Chemical | 17718 | TC-E 5003 ≥98% | 500mg | $384 | 2024-03-01 | Buy |
| CSNpharm | CSN23150 | TC-E5003 | 10mg | $30 | 2021-12-16 | Buy |
| CSNpharm | CSN23150 | TC-E5003 | 100mg | $115 | 2021-12-16 | Buy |
Properties
Melting point :191-192 °C
Boiling point :704.2±60.0 °C(Predicted)
Density :1.504±0.06 g/cm3(Predicted)
storage temp. :-20°C (des.)
solubility :Soluble in DMSO (up to 50 mg/ml).
form :solid
pka :11.56±0.70(Predicted)
color :Brown
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
Boiling point :704.2±60.0 °C(Predicted)
Density :1.504±0.06 g/cm3(Predicted)
storage temp. :-20°C (des.)
solubility :Soluble in DMSO (up to 50 mg/ml).
form :solid
pka :11.56±0.70(Predicted)
color :Brown
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
Safety Information
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Description
TC-E 5003 is an inhibitor of protein arginine methyltransferase 1 (PRMT1; IC50 = 1.5 μM for human PRMT1 in a methylation assay). It is selective for PRMT1 over PRMT4/CARM1 and SET7/9 methyltransferases, with less than 5% inhibition at a concentration of 50 μM for SET7/9. TC-E 5003 inhibits growth of MCF-7a breast cancer and LNCaP prostate cancer cells (GI50s = 1.97 and 4.49 μM, respectively) and decreases androgen-dependent gene transcription in vitro. TC-E 5003 (80 mg/kg) also has antimalarial properties and eradicates P. berghei in mice.Related product price
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