N,N'-[Sulfonylbis(1,4-phenylene)]bis(chloroacetamide)
- $13 - $1200
- Product name: N,N'-[Sulfonylbis(1,4-phenylene)]bis(chloroacetamide)
- CAS: 17328-16-4
- MF: C16H14Cl2N2O4S
- MW: 401.26
- EINECS:
- MDL Number:MFCD00028183
- Synonyms:4',4'''-Sulfonylbis(α-chloroacetanilide);Bis[4-(chloroacetylamino)phenyl] sulfone;N,N'-[Sulfonylbis(1,4-phenylene)]bis(chloroacetamide);TC-E 5003;N,N'-(Sulfonyldi-4,1-phenylene)bis(2-chloroacetamide);N'-(Sulfonyldi-4;1-phenylene)bis(2-chloroacetamide);TC-E 5003 (NSC-30176)
23 prices
Selected condition:
Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- CSNpharm
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 003
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 50
- 100mg
- 250mg
- 500mg
- 002
- 5g
- 001
- ManufacturerAK Scientific
- Product number5881CA
- Product descriptionSulfone,bis((4-chloroacetylamino)phenyl)
- Packaging5g
- Price$802
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA169549
- Product descriptionTc-e5003 95+%
- Packaging1mg
- Price$13
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA169549
- Product descriptionTc-e5003 95+%
- Packaging5mg
- Price$28
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA169549
- Product descriptionTc-e5003 95+%
- Packaging10mg
- Price$42
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA169549
- Product descriptionTc-e5003 95+%
- Packaging25mg
- Price$71
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA169549
- Product descriptionTc-e5003 95+%
- Packaging50mg
- Price$106
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA169549
- Product descriptionTc-e5003 95+%
- Packaging100mg
- Price$160
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA169549
- Product descriptionTc-e5003 95+%
- Packaging250mg
- Price$272
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberHCH0121427
- Product description4',4''-SULFONYLBIS-(2-CHLOROACETANILIDE) 95.00%
- Packaging5MG
- Price$498.8
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7750
- Product descriptionTC-E5003
- Packaging50mg
- Price$71
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number17718
- Product descriptionTC-E 5003 ≥95%
- Packaging25mg
- Price$44
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17718
- Product descriptionTC-E 5003 ≥95%
- Packaging50mg
- Price$70
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17718
- Product descriptionTC-E 5003 ≥95%
- Packaging100mg
- Price$130
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17718
- Product descriptionTC-E 5003 ≥98%
- Packaging500mg
- Price$384
- Updated2024-03-01
- Buy
- ManufacturerCSNpharm
- Product numberCSN23150
- Product descriptionTC-E5003
- Packaging10mg
- Price$30
- Updated2021-12-16
- Buy
- ManufacturerCSNpharm
- Product numberCSN23150
- Product descriptionTC-E5003
- Packaging100mg
- Price$115
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 5881CA | Sulfone,bis((4-chloroacetylamino)phenyl) | 5g | $802 | 2021-12-16 | Buy |
Ambeed | A169549 | Tc-e5003 95+% | 1mg | $13 | 2021-12-16 | Buy |
Ambeed | A169549 | Tc-e5003 95+% | 5mg | $28 | 2021-12-16 | Buy |
Ambeed | A169549 | Tc-e5003 95+% | 10mg | $42 | 2021-12-16 | Buy |
Ambeed | A169549 | Tc-e5003 95+% | 25mg | $71 | 2021-12-16 | Buy |
Ambeed | A169549 | Tc-e5003 95+% | 50mg | $106 | 2021-12-16 | Buy |
Ambeed | A169549 | Tc-e5003 95+% | 100mg | $160 | 2021-12-16 | Buy |
Ambeed | A169549 | Tc-e5003 95+% | 250mg | $272 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | HCH0121427 | 4',4''-SULFONYLBIS-(2-CHLOROACETANILIDE) 95.00% | 5MG | $498.8 | 2021-12-16 | Buy |
ApexBio Technology | B7750 | TC-E5003 | 50mg | $71 | 2021-12-16 | Buy |
Cayman Chemical | 17718 | TC-E 5003 ≥95% | 25mg | $44 | 2024-03-01 | Buy |
Cayman Chemical | 17718 | TC-E 5003 ≥95% | 50mg | $70 | 2024-03-01 | Buy |
Cayman Chemical | 17718 | TC-E 5003 ≥95% | 100mg | $130 | 2024-03-01 | Buy |
Cayman Chemical | 17718 | TC-E 5003 ≥98% | 500mg | $384 | 2024-03-01 | Buy |
CSNpharm | CSN23150 | TC-E5003 | 10mg | $30 | 2021-12-16 | Buy |
CSNpharm | CSN23150 | TC-E5003 | 100mg | $115 | 2021-12-16 | Buy |
Properties
Melting point :191-192 °C
Boiling point :704.2±60.0 °C(Predicted)
Density :1.504±0.06 g/cm3(Predicted)
storage temp. :-20°C (des.)
solubility :Soluble in DMSO (up to 50 mg/ml).
form :solid
pka :11.56±0.70(Predicted)
color :Brown
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
Boiling point :704.2±60.0 °C(Predicted)
Density :1.504±0.06 g/cm3(Predicted)
storage temp. :-20°C (des.)
solubility :Soluble in DMSO (up to 50 mg/ml).
form :solid
pka :11.56±0.70(Predicted)
color :Brown
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
Safety Information
Symbol(GHS): | ||||||||
---|---|---|---|---|---|---|---|---|
Signal word: | ||||||||
Hazard statements: |
|
|||||||
Precautionary statements: |
|
Description
TC-E 5003 is an inhibitor of protein arginine methyltransferase 1 (PRMT1; IC50 = 1.5 μM for human PRMT1 in a methylation assay). It is selective for PRMT1 over PRMT4/CARM1 and SET7/9 methyltransferases, with less than 5% inhibition at a concentration of 50 μM for SET7/9. TC-E 5003 inhibits growth of MCF-7a breast cancer and LNCaP prostate cancer cells (GI50s = 1.97 and 4.49 μM, respectively) and decreases androgen-dependent gene transcription in vitro. TC-E 5003 (80 mg/kg) also has antimalarial properties and eradicates P. berghei in mice.Related product price
- Troglitazone
$55-2318 - Cantharidin
$18.78-681.45 - Sunitinib Malate
$6-1593.9
Suppliers and manufacturers
ATK CHEMICAL COMPANY LIMITED
Accela ChemBio Inc.
Fuxin Pharmaceutical
TargetMol Chemicals Inc.
Career Henan Chemica Co
Hangzhou MolCore BioPharmatech Co.,Ltd.
Shanghai Acmec Biochemical Technology Co., Ltd.
Aladdin Scientific
Amadis Chemical Company Limited
Shanghai Aladdin Bio-Chem Technology Co.,LTD