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ChemicalBook >> CAS DataBase List >> E3 ligase Ligand-Linker Conjugates 7 Free Base

E3 ligase Ligand-Linker Conjugates 7 Free Base

E3 ligase Ligand-Linker Conjugates 7 Free Base price.
  • $452 - $1000
  • Product name: E3 ligase Ligand-Linker Conjugates 7 Free Base
  • CAS: 2010159-57-4
  • MF: C32H49N5O8S
  • MW: 663.83
  • EINECS:
  • MDL Number:MFCD31656715
  • Synonyms:E3 ligase Ligand-Linker Conjugates 7 Free Base;VH032-PEG4-NH2;VHL Ligand-Linker Conjugates 4;PROTACs Related Compound 8;(S,R. S)-AHPC-PEG4-amine hydrochloride salt;L-Prolinamide, N-(14-amino-1-oxo-3,6,9,12-tetraoxatetradec-1-yl)-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-;(S,R,S)-AHPC-PEG4-NH2(E3 ligase Ligand-Linker Conjugates 7);(2S,4R)-1-((S)-17-amino-2-(tert-butyl)-4-oxo-6,9,12,15-tetraoxa-3-azaheptadecanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
Price4 Properties Safety Information Description
4 prices
Selected condition：
Brand
  • BroadPharm
  • DC Chemicals
  • Sigma-Aldrich
Package
  • 003
  • 250mg
  • 50mg
  • 002
  • ManufacturerBroadPharm
  • Product numberBP-24446
  • Product description(S,R.S)-AHPC-PEG4-aminehydrochloridesalt 98%
  • Packaging250mg
  • Price$960
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product number027595
  • Product description(S,R,S)-AHPC-PEG4-NH2(E3ligaseLigand-LinkerConjugates7)
  • Packaging002
  • Price$500
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product number027595
  • Product description(S,R,S)-AHPC-PEG4-NH2(E3ligaseLigand-LinkerConjugates7)
  • Packaging003
  • Price$1000
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number901848
  • Product description(S,R,S)-AHPC-PEG4-NH2 hydrochloride ≥95%
  • Packaging50mg
  • Price$452
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
BroadPharm BP-24446 (S,R.S)-AHPC-PEG4-aminehydrochloridesalt 98% 250mg $960 2021-12-16 Buy
DC Chemicals 027595 (S,R,S)-AHPC-PEG4-NH2(E3ligaseLigand-LinkerConjugates7) 002 $500 2021-12-16 Buy
DC Chemicals 027595 (S,R,S)-AHPC-PEG4-NH2(E3ligaseLigand-LinkerConjugates7) 003 $1000 2021-12-16 Buy
Sigma-Aldrich 901848 (S,R,S)-AHPC-PEG4-NH2 hydrochloride ≥95% 50mg $452 2024-03-01 Buy

Properties

Boiling point :901.7±65.0 °C(Predicted)
Density :1.230±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Soluble in Water, DMSO, Methanol
pka :13.54±0.46(Predicted)
form :Solid
color :White to off-white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

(S, R, S)-AHPC-PEG4-amine is a PROTAC linker that incorporates an E3 ligase ligand with a PEG4 unit to empower drug research & discovery. The amine group is reactive with NHS ester or carboxylic acid.

Suppliers and manufacturers

Xian confluore Biological Technology Co., Ltd.
(S,R,S)-AHPC-PEG4-NH2
$0.00 /100mg
(S,R,S)-AHPC-PEG4-NH2 CAS:2010159-57-4
TargetMol Chemicals Inc.
LEAPCHEM CO., LTD.
Jilin Chinese Academy of Sciences-yanshen Technology
Aladdin Scientific Sigma-Aldrich Shanghai Chaolan Chemical Technology Center Xi'an Confluore Biological Technology Co., Ltd. Jiangsu aikang biomedical research and development co., LTD Jilin Province Woda Biotechnology Co., Ltd.