Welcome to chemicalbook!
400-158-6606
Inquriy
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook >> CAS DataBase List >> N-(4-Ethoxyphenyl)-4-(2-methylimidazo[1,2-a]pyridin-3-yl)thiazol-2-amine

N-(4-Ethoxyphenyl)-4-(2-methylimidazo[1,2-a]pyridin-3-yl)thiazol-2-amine

N-(4-Ethoxyphenyl)-4-(2-methylimidazo[1,2-a]pyridin-3-yl)thiazol-2-amine price.
  • $32 - $4725
  • Product name: N-(4-Ethoxyphenyl)-4-(2-methylimidazo[1,2-a]pyridin-3-yl)thiazol-2-amine
  • CAS: 315703-52-7
  • MF: C19H18N4OS
  • MW: 350.44
  • EINECS:
  • MDL Number:MFCD01044465
  • Synonyms:N-(4-Ethoxyphenyl)-4-(2-methylimidazo[1,2-a]pyridin-3-yl)thiazol-2-amine;Hh Signaling Antagonist VII, JK184;JK 184;N-(4-Ethoxyphenyl)-4-(2-methylimidazo[1,2-a]pyridin-3-yl)-2-thiazolamine;2-ThiazolaMine, N-(4-ethoxyphenyl)-4-(2-MethyliMidazo[1,2-a]pyridin-3-yl)-;Hh Signaling Antagonist VII, JK184 - CAS 315703-52-7 - Calbiochem;CS-2369;JK184 (JK-184
30 prices
Selected condition:
Brand
  • AK Scientific
  • ApexBio Technology
  • Axon Medchem
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 25
  • 50mg
  • 100mg
  • 250mg
  • 5
  • 1g
  • ManufacturerAK Scientific
  • Product number3425AB
  • Product descriptionN-(4-Ethoxyphenyl)-4-(2-methylimidazo[1,2-a]pyridin-3-yl)thiazol-2-amine
  • Packaging1g
  • Price$1246
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number3425AB
  • Product descriptionN-(4-Ethoxyphenyl)-4-(2-methylimidazo[1,2-a]pyridin-3-yl)thiazol-2-amine
  • Packaging25mg
  • Price$263
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number3425AB
  • Product descriptionN-(4-Ethoxyphenyl)-4-(2-methylimidazo[1,2-a]pyridin-3-yl)thiazol-2-amine
  • Packaging5mg
  • Price$113
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8652
  • Product descriptionJK184
  • Packaging5mg
  • Price$87
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8652
  • Product descriptionJK184
  • Packaging10mg
  • Price$127
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8652
  • Product descriptionJK184
  • Packaging50mg
  • Price$554
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8652
  • Product descriptionJK184
  • Packaging100mg
  • Price$992
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2654
  • Product descriptionJK184 100%
  • Packaging50mg
  • Price$308
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number15265
  • Product descriptionJK 184 ≥99%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15265
  • Product descriptionJK 184 ≥99%
  • Packaging5mg
  • Price$62
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15265
  • Product descriptionJK 184 ≥99%
  • Packaging10mg
  • Price$109
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15265
  • Product descriptionJK 184 ≥99%
  • Packaging50mg
  • Price$472
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM175661
  • Product descriptionN-(4-Ethoxyphenyl)-4-(2-methylimidazo[1,2-a]pyridin-3-yl)thiazol-2-amine 95%
  • Packaging100mg
  • Price$386
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6080
  • Product descriptionJK184 99.95%
  • Packaging5mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6080
  • Product descriptionJK184 99.95%
  • Packaging10mg
  • Price$96
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6080
  • Product descriptionJK184 99.95%
  • Packaging50mg
  • Price$396
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 3425AB N-(4-Ethoxyphenyl)-4-(2-methylimidazo[1,2-a]pyridin-3-yl)thiazol-2-amine 1g $1246 2021-12-16 Buy
AK Scientific 3425AB N-(4-Ethoxyphenyl)-4-(2-methylimidazo[1,2-a]pyridin-3-yl)thiazol-2-amine 25mg $263 2021-12-16 Buy
AK Scientific 3425AB N-(4-Ethoxyphenyl)-4-(2-methylimidazo[1,2-a]pyridin-3-yl)thiazol-2-amine 5mg $113 2021-12-16 Buy
ApexBio Technology A8652 JK184 5mg $87 2021-12-16 Buy
ApexBio Technology A8652 JK184 10mg $127 2021-12-16 Buy
ApexBio Technology A8652 JK184 50mg $554 2021-12-16 Buy
ApexBio Technology A8652 JK184 100mg $992 2021-12-16 Buy
Axon Medchem Axon2654 JK184 100% 50mg $308 2021-12-16 Buy
Cayman Chemical 15265 JK 184 ≥99% 1mg $32 2024-03-01 Buy
Cayman Chemical 15265 JK 184 ≥99% 5mg $62 2024-03-01 Buy
Cayman Chemical 15265 JK 184 ≥99% 10mg $109 2024-03-01 Buy
Cayman Chemical 15265 JK 184 ≥99% 50mg $472 2024-03-01 Buy
Chemenu CM175661 N-(4-Ethoxyphenyl)-4-(2-methylimidazo[1,2-a]pyridin-3-yl)thiazol-2-amine 95% 100mg $386 2021-12-16 Buy
ChemScene CS-6080 JK184 99.95% 5mg $60 2021-12-16 Buy
ChemScene CS-6080 JK184 99.95% 10mg $96 2021-12-16 Buy
ChemScene CS-6080 JK184 99.95% 50mg $396 2021-12-16 Buy

Properties

storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :DMSO: ≥20mg/mL
form :powder
color :off-white to light brown

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger GHS hazard pictograms P280, P305+P351+P338, P310
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

JK 184 is an imidazopyridine derivative that inhibits downstream hedgehog signaling, preventing Gli-dependent transcriptional activity (IC50 = 30 nM). It does so by inhibiting alcohol dehydrogenase 7 (IC50 = 210 nM) and depolymerizing microtubules, preventing their assembly, which is crucial for Gli function. JK 184 exhibits antiproliferative activity in a range of cancer cell lines (L3.6pl, Panc 05.04, BxPC3, D283 med, Daoy; GI50s = 3-21 nM) and in L3.6pl and BxPC3 pancreatic cancer xenograft models (0.2 mg/mouse/day).

More related product prices

4-Aminodiphenylamine FORMANILIDE N-Methylformamide

Related product price