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ChemicalBook >> CAS DataBase List >> 11-OXO-PROSTA-5Z,12E,14Z-TRIEN-1-OIC ACID

11-OXO-PROSTA-5Z,12E,14Z-TRIEN-1-OIC ACID

11-OXO-PROSTA-5Z,12E,14Z-TRIEN-1-OIC ACID price.
  • $87 - $1189
  • Product name: 11-OXO-PROSTA-5Z,12E,14Z-TRIEN-1-OIC ACID
  • CAS: 596104-94-8
  • MF: C20H30O3
  • MW: 318.45
  • EINECS:
  • MDL Number:MFCD03412003
  • Synonyms:11-OXO-PROSTA-5Z,12E,14Z-TRIEN-1-OIC ACID;9,10-DIHYDRO-15-DEOXY-DELTA12,14-PROSTAGLANDIN J2;CAY10410;9,10-dihydro-15-deoxy-Δ12,14-Prostaglandin J2;AFBJLDUEEOOVHL-WKELIDJCSA-N;Prosta-5,12,14-trien-1-oic acid, 11-oxo-, (5Z,12E,14Z)-;CAY10410,CAY-10410
4 prices
Selected condition:
Brand
  • Cayman Chemical
Package
  • 500μg
  • 1mg
  • 5mg
  • 10mg
  • ManufacturerCayman Chemical
  • Product number18590
  • Product descriptionCAY10410 ≥98% (isomer mixture)
  • Packaging500μg
  • Price$87
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18590
  • Product descriptionCAY10410 ≥98% (isomer mixture)
  • Packaging1mg
  • Price$163
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18590
  • Product descriptionCAY10410 ≥98% (isomer mixture)
  • Packaging5mg
  • Price$680
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18590
  • Product descriptionCAY10410 ≥98% (isomer mixture)
  • Packaging10mg
  • Price$1189
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Cayman Chemical 18590 CAY10410 ≥98% (isomer mixture) 500μg $87 2024-03-01 Buy
Cayman Chemical 18590 CAY10410 ≥98% (isomer mixture) 1mg $163 2024-03-01 Buy
Cayman Chemical 18590 CAY10410 ≥98% (isomer mixture) 5mg $680 2024-03-01 Buy
Cayman Chemical 18590 CAY10410 ≥98% (isomer mixture) 10mg $1189 2024-03-01 Buy

Properties

storage temp. :Store at -20°C
solubility :DMF: 100 mg/ml; DMSO: 20 mg/ml; Ethanol: 75 mg/ml; PBS (7.2): 2.7 mg/ml

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger GHS hazard pictograms P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H336 May cause drowsiness or dizziness Specific target organ toxicity,single exposure; Narcotic effects Category 3 Warning P261, P271, P304+P340, P312,P403+P233, P405, P501
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242 Use only non-sparking tools.
P243 Take precautionary measures against static discharge.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P370+P378 In case of fire: Use … for extinction.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P403+P235 Store in a well-ventilated place. Keep cool.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

CAY10410 is an analog of prostaglandin D2/prostaglandin J2 (PGD2/PGJ2) with structural modifications intended to give it PPARγ ligand activity and resistance to metabolism. 15-deoxy-Δ12,14-PGJ2 has been shown to be a potent ligand for PPARγ. Metabolism of the cyclopentenone prostaglandins PGA2, PGJ2, and Δ12-PGJ2 occurs via glutathione addition across the α,β unsaturated enone. CAY10410 was designed as an analog of the PPARγ-binding prostaglandins which could not undergo this conjugation reaction. In human neuroblastoma SH-SY5Y cells, CAY10410 was not cytotoxic at up to 25 μM. It also failed to covalently modify thioredoxin or induce oxidative stress at 50 μM.

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