3-(4-Bromophenyl)-3-(trifluoromethyl)-3H-diazirine
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- $239 - $2705
- Product name: 3-(4-Bromophenyl)-3-(trifluoromethyl)-3H-diazirine
- CAS: 952143-02-1
- MF: C8H4BrF3N2
- MW: 265.03
- EINECS:
- MDL Number:
- Synonyms:3-(4-Bromophenyl)-3-(trifluoromethyl)-3H-diazirine;3H-Diazirine, 3-(4-bromophenyl)-3-(trifluoromethyl)-
2 prices
Selected condition：
Brand
- AK Scientific
- Sigma-Aldrich
Package
- 50mg
- 2.5g
- ManufacturerAK Scientific
- Product number6535CX
- Product description3-(4-Bromophenyl)-3-(trifluoromethyl)-3H-diazirine
- Packaging2.5g
- Price$2705
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product number906298
- Product description3-(4-Bromophenyl)-3-(trifluoromethyl)-3H-diazirine
- Packaging50mg
- Price$239
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 6535CX | 3-(4-Bromophenyl)-3-(trifluoromethyl)-3H-diazirine | 2.5g | $2705 | 2021-12-16 | Buy |
| Sigma-Aldrich | 906298 | 3-(4-Bromophenyl)-3-(trifluoromethyl)-3H-diazirine | 50mg | $239 | 2024-03-01 | Buy |
Properties
Boiling point :228.5±50.0 °C(Predicted)
Density :1.81±0.1 g/cm3(Predicted)
storage temp. :2-8°C
Density :1.81±0.1 g/cm3(Predicted)
storage temp. :2-8°C
Safety Information
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| Signal word: | Danger | |||||||||||||||||||||
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Description
3-(4-Bromophenyl)-3-(trifluoromethyl)-3H-diazirine is a Suzuki-Miyaura (S?M)-compatible building block tailored for the design of photoaffinity probes (PAPs). Photoaffinity labeling (PAL) is of growing interest in chemical biology and drug discovery research for use in protein profiling; covalent inhibitors; protein-protein interactions and complexes; and target engagement, identification, or validation studies. Diazirines are desirable photoactivable groups for chemical probes; however, their installation is not always straightforward. In response, diazirine-tolerant S-M coupling conditions were developed by Ichiishi, et al, using 3-(4-bromophenyl)-3-(trifluoromethyl)-3H-diazirine and shown to be efficient and scalable with minimal perturbation of the diazirine.Suppliers and manufacturers
Aladdin Scientific
Shanghai Haohong Pharmaceutical Co., Ltd.
ChemShuttle, Inc.
Sigma-Aldrich
Taizhou GreenChem Pharmaceutical Co., Ltd.
Ningbo Benkang jishi Pharmaceutical Technology Co., Ltd.
Block Chemical Technology (Shanghai) Co., LTD
Milestone Chemical Wuxi Co.,Ltd
Tianjin Kaimu Chemical Technology Co., LTD
Bide Pharmatech Ltd.