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ChemicalBook >> CAS DataBase List >> AD57 (hydrochloride)

AD57 (hydrochloride)

AD57 (hydrochloride) price.
  • $62 - $543
  • Product name: AD57 (hydrochloride)
  • CAS: 2320261-72-9
  • MF: C22H21ClF3N7O
  • MW: 491.8966496
  • EINECS:
  • MDL Number:
  • Synonyms:AD57 (hydrochloride);N-[4-[4-amino-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl]phenyl]-N'-[3-(trifluoromethyl)phenyl]-urea,monohydrochloride
Price6 Properties Safety Information Description
6 prices
Selected condition：
Brand
  • ApexBio Technology
  • Cayman Chemical
Package
  • 1mg
  • 5mg
  • 10mg
  • ManufacturerApexBio Technology
  • Product numberC3080
  • Product descriptionAD57(hydrochloride)
  • Packaging1mg
  • Price$68
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3080
  • Product descriptionAD57(hydrochloride)
  • Packaging5mg
  • Price$307
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3080
  • Product descriptionAD57(hydrochloride)
  • Packaging10mg
  • Price$543
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number13975
  • Product descriptionAD57 (hydrochloride) ≥98%
  • Packaging1mg
  • Price$62
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13975
  • Product descriptionAD57 (hydrochloride) ≥98%
  • Packaging5mg
  • Price$270
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13975
  • Product descriptionAD57 (hydrochloride) ≥98%
  • Packaging10mg
  • Price$477
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ApexBio Technology C3080 AD57(hydrochloride) 1mg $68 2021-12-16 Buy
ApexBio Technology C3080 AD57(hydrochloride) 5mg $307 2021-12-16 Buy
ApexBio Technology C3080 AD57(hydrochloride) 10mg $543 2021-12-16 Buy
Cayman Chemical 13975 AD57 (hydrochloride) ≥98% 1mg $62 2024-03-01 Buy
Cayman Chemical 13975 AD57 (hydrochloride) ≥98% 5mg $270 2024-03-01 Buy
Cayman Chemical 13975 AD57 (hydrochloride) ≥98% 10mg $477 2024-03-01 Buy

Properties

storage temp. :Store at -20°C
solubility :DMF: 14 mg/ml; DMF:PBS (pH 7.2) (1:4): 0.20 mg/ml; DMSO: 10 mg/ml; Ethanol: 5 mg/ml
form :A crystalline solid

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Complex diseases, like cancer, may best be countered by compounds that affect multiple targets. AD57 is a polypharmacological cancer therapeutic, in that it is designed to modulate multiple targets related to cancer.1 In Drosophila, it potently inhibits the receptor tyrosine kinase RET (IC50 = 2 nM) and reduces the activity of numerous other kinases by more than 80% when given at 1 μM.1 Most notably, AD57 interferes with kinases downstream of RET, including Src, Raf, and S6K, providing further efficacy in preventing signaling leading to invasion, proliferation, and metabolism relevant to cancer.1

Suppliers and manufacturers

Shanghai Chaolan Chemical Technology Center Shanghai Dongyang Biotechnology Co., Ltd. ChemeGen(Shanghai) Biotechnology Co.,Ltd. Nanjing Tengyi Biotechnology Co., Ltd Shanghai Yifei Biotechnology Co. , Ltd. https://hanhongsci.com/ TargetMol Chemicals Inc.