AZ 12216052
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- $38 - $1216.22
- Product name: AZ 12216052
- CAS: 1290628-31-7
- MF: C19H22BrNOS
- MW: 392.35308
- EINECS:
- MDL Number:MFCD20926426
- Synonyms:AZ 12216052;2-[[(4-Bromophenyl)methyl]thio]-N-[4-(1-methylpropyl)phenyl]acetamide;AZ12216052 >=98% (HPLC);Acetamide, 2-[[(4-bromophenyl)methyl]thio]-N-[4-(1-methylpropyl)phenyl]-
12 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- Cayman Chemical
- Tocris
- TRC
- Usbiological
Package
- 50
- 1mg
- 5mg
- 10MG
- 25mg
- 10
- 50MG
- 100mg
- ManufacturerAK Scientific
- Product number7587DW
- Product description2-[(4-Bromophenyl)methylsulfanyl]-N-(4-butan-2-ylphenyl)acetamide
- Packaging1mg
- Price$140
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number7587DW
- Product description2-[(4-Bromophenyl)methylsulfanyl]-N-(4-butan-2-ylphenyl)acetamide
- Packaging5mg
- Price$212
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0004379
- Product descriptionAZ-12216052 98.00%
- Packaging10MG
- Price$260.4
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0004379
- Product descriptionAZ-12216052 98.00%
- Packaging50MG
- Price$1216.22
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number29460
- Product descriptionAZ 12216052
- Packaging1mg
- Price$38
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number29460
- Product descriptionAZ 12216052
- Packaging5mg
- Price$104
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number29460
- Product descriptionAZ 12216052
- Packaging10mg
- Price$184
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number29460
- Product descriptionAZ 12216052
- Packaging25mg
- Price$412
- Updated2024-03-01
- Buy
- ManufacturerTocris
- Product number4832
- Product descriptionAZ12216052 ≥97%(HPLC)
- Packaging10
- Price$170
- Updated2021-12-16
- Buy
- ManufacturerTocris
- Product number4832
- Product descriptionAZ12216052 ≥97%(HPLC)
- Packaging50
- Price$710
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberA808215
- Product descriptionAZ12216052
- Packaging100mg
- Price$1200
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number254696
- Product descriptionAZ 12216052
- Packaging10mg
- Price$409
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 7587DW | 2-[(4-Bromophenyl)methylsulfanyl]-N-(4-butan-2-ylphenyl)acetamide | 1mg | $140 | 2021-12-16 | Buy |
| AK Scientific | 7587DW | 2-[(4-Bromophenyl)methylsulfanyl]-N-(4-butan-2-ylphenyl)acetamide | 5mg | $212 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0004379 | AZ-12216052 98.00% | 10MG | $260.4 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0004379 | AZ-12216052 98.00% | 50MG | $1216.22 | 2021-12-16 | Buy |
| Cayman Chemical | 29460 | AZ 12216052 | 1mg | $38 | 2024-03-01 | Buy |
| Cayman Chemical | 29460 | AZ 12216052 | 5mg | $104 | 2024-03-01 | Buy |
| Cayman Chemical | 29460 | AZ 12216052 | 10mg | $184 | 2024-03-01 | Buy |
| Cayman Chemical | 29460 | AZ 12216052 | 25mg | $412 | 2024-03-01 | Buy |
| Tocris | 4832 | AZ12216052 ≥97%(HPLC) | 10 | $170 | 2021-12-16 | Buy |
| Tocris | 4832 | AZ12216052 ≥97%(HPLC) | 50 | $710 | 2021-12-16 | Buy |
| TRC | A808215 | AZ12216052 | 100mg | $1200 | 2021-12-16 | Buy |
| Usbiological | 254696 | AZ 12216052 | 10mg | $409 | 2021-12-16 | Buy |
Properties
Boiling point :526.9±45.0 °C(Predicted)
Density :1.323±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO: soluble
form :A crystalline solid
pka :13.70±0.70(Predicted)
color :White to off-white
Density :1.323±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO: soluble
form :A crystalline solid
pka :13.70±0.70(Predicted)
color :White to off-white
Safety Information
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Description
AZ 12216052 is a positive allosteric modulator of metabotropic glutamate receptor 8 (mGluR8). It potentiates glutamate-induced [35S]GTPγS binding in GHEK cells expressing human mGluR8b (EC50 = 1 μM). In a cell-based model of Parkinson’s disease, AZ 12216052 inhibits MPP+-induced decreases in the viability of undifferentiated SH-SY5Y cells when used at concentrations ranging from 0.001 to 1 μM and in retinoic acid-differentiated SH-SY5Y cells at 0.1 and 1 μM. AZ 12216052 (10 mg/kg) increases the time spent in the open areas of the elevated zero maze and reduces the acoustic startle response in mice, indicating anxiolytic-like activity in response to avoidable and unavoidable anxiogenic stimuli, respectively.Suppliers and manufacturers
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