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ChemicalBook >> CAS DataBase List >> CAY10499

CAY10499

CAY10499 price.
  • $16 - $235
  • Product name: CAY10499
  • CAS: 359714-55-9
  • MF: C18H17N3O5
  • MW: 355.34
  • EINECS:
  • MDL Number:MFCD12912259
  • Synonyms:CAY10499;QTENHWTVRQKWRI-UHFFFAOYSA-N;CAY10499 Exclusive;Inhibitor,inhibit,MAGLIN5,MAGL IN 5,FAAH,Fatty acid amide hydrolase,Monoacylglycerol lipase,MAGL;Carbamic acid, N-[4-(5-methoxy-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-2-methylphenyl]-, phenylmethyl ester;Benzyl (4-(5-methoxy-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-2-methylphenyl)carbamate
6 prices
Selected condition:
Brand
  • AK Scientific
  • ApexBio Technology
  • Cayman Chemical
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • ManufacturerAK Scientific
  • Product number4276CR
  • Product descriptionBenzylN-[4-(5-methoxy-2-oxo-1,3,4-oxadiazol-3-yl)-2-methylphenyl]carbamate
  • Packaging5mg
  • Price$167
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7841
  • Product descriptionCAY10499
  • Packaging10mg
  • Price$154
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10007875
  • Product descriptionCAY10499 ≥98%
  • Packaging1mg
  • Price$16
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10007875
  • Product descriptionCAY10499 ≥98%
  • Packaging5mg
  • Price$63
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10007875
  • Product descriptionCAY10499 ≥98%
  • Packaging10mg
  • Price$109
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10007875
  • Product descriptionCAY10499 ≥98%
  • Packaging25mg
  • Price$235
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 4276CR BenzylN-[4-(5-methoxy-2-oxo-1,3,4-oxadiazol-3-yl)-2-methylphenyl]carbamate 5mg $167 2021-12-16 Buy
ApexBio Technology B7841 CAY10499 10mg $154 2021-12-16 Buy
Cayman Chemical 10007875 CAY10499 ≥98% 1mg $16 2024-03-01 Buy
Cayman Chemical 10007875 CAY10499 ≥98% 5mg $63 2024-03-01 Buy
Cayman Chemical 10007875 CAY10499 ≥98% 10mg $109 2024-03-01 Buy
Cayman Chemical 10007875 CAY10499 ≥98% 25mg $235 2024-03-01 Buy

Properties

Density :1.31±0.1 g/cm3(Predicted)
solubility :Soluble in DMSO
form :crystalline solid
pka :13.31±0.70(Predicted)
color :Off-white to yellow

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

CAY10499 is a non-selective lipase inhibitor (IC50s = 144, 90, and 14 nM for human recombinant MAGL, HSL, and FAAH, respectively). It also inhibits ATGL, DAGLa, ABHD6, and CES1 by 95, 60, 90, and 95%, respectively, when used at a concentration of 5 mM. CAY10499 inhibits the growth of MCF-7, MDA-MB-231, COV318, and OVCAR-3 cancer cells (IC50s = 4.2, 46, 106.7, and 79.8 μM, respectively). In vivo, CAY10499 reduces FRUC diet- and AIN-93M diet-induced increases in cytosolic lipase activity in rats.