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ChemicalBook >> CAS DataBase List >> CAY10606

CAY10606

CAY10606 price.
  • $50 - $495.91
  • Product name: CAY10606
  • CAS: 1159576-98-3
  • MF: C22H18ClNO3
  • MW: 379.84
  • EINECS:
  • MDL Number:MFCD18382112
  • Synonyms:CAY10606;2-[(3-Chlorophenyl)methyl]-5-hydroxy-1H-benz[g]indole-3-carboxylic acid, ethyl ester;1H-Benz[g]indole-3-carboxylic acid, 2-[(3-chlorophenyl)methyl]-5-hydroxy-, ethyl ester
7 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • Cayman Chemical
  • TRC
Package
  • 1mg
  • 2.5mg
  • 5MG
  • 10mg
  • ManufacturerAK Scientific
  • Product number1339AH
  • Product description2-[(3-Chlorophenyl)methyl]-5-hydroxy-1H-benz[g]indole-3-carboxylicacid,ethylester
  • Packaging1mg
  • Price$166
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHCH0069390
  • Product description2-((3-CHLOROPHENYL)METHYL)-5-HYDROXY-1H-BENZ(G)INDOLE-3-CARBOXYLIC ACID, ETHYL ESTER 95.00%
  • Packaging5MG
  • Price$495.91
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number13381
  • Product descriptionCAY10606 ≥98%
  • Packaging1mg
  • Price$62
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13381
  • Product descriptionCAY10606 ≥98%
  • Packaging5mg
  • Price$270
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13381
  • Product descriptionCAY10606 ≥98%
  • Packaging10mg
  • Price$392
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberB405078
  • Product description2-[(3-chlorophenyl)methyl]-5-hydroxy-1H-benz[g]indole-3-carboxylicacid,ethylester
  • Packaging1mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberB405078
  • Product description2-[(3-chlorophenyl)methyl]-5-hydroxy-1H-benz[g]indole-3-carboxylicacid,ethylester
  • Packaging2.5mg
  • Price$100
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1339AH 2-[(3-Chlorophenyl)methyl]-5-hydroxy-1H-benz[g]indole-3-carboxylicacid,ethylester 1mg $166 2021-12-16 Buy
American Custom Chemicals Corporation HCH0069390 2-((3-CHLOROPHENYL)METHYL)-5-HYDROXY-1H-BENZ(G)INDOLE-3-CARBOXYLIC ACID, ETHYL ESTER 95.00% 5MG $495.91 2021-12-16 Buy
Cayman Chemical 13381 CAY10606 ≥98% 1mg $62 2024-03-01 Buy
Cayman Chemical 13381 CAY10606 ≥98% 5mg $270 2024-03-01 Buy
Cayman Chemical 13381 CAY10606 ≥98% 10mg $392 2021-12-16 Buy
TRC B405078 2-[(3-chlorophenyl)methyl]-5-hydroxy-1H-benz[g]indole-3-carboxylicacid,ethylester 1mg $50 2021-12-16 Buy
TRC B405078 2-[(3-chlorophenyl)methyl]-5-hydroxy-1H-benz[g]indole-3-carboxylicacid,ethylester 2.5mg $100 2021-12-16 Buy

Properties

Melting point :222 °C(Solv: ethyl acetate (141-78-6); cyclohexane (110-82-7))
Boiling point :624.2±55.0 °C(Predicted)
Density :1.355±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 25 mg/ml; DMSO: 25 mg/ml; Ethanol: 20 mg/ml
form :A crystalline solid
pka :8.86±0.30(Predicted)

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

5-Lipoxygenase (5-LO) initiates the synthesis of leukotrienes (LTs) from arachidonic acid, primarily in certain leukocyte populations. CAY10606 is a potent, reversible inhibitor of 5-LO, both in cell-free assays (IC50 = 86 nM) and in intact neutrophils (IC50 = 230 nM). It prevents the production of LTs in whole blood, whether 5-LO is activated with the calcium ionophore A23187 (IC50 = 1.6 μM) or formyl peptide (fMLP) following priming with lipopolysaccharide (IC50 = 830 nM). In rats subjected to carrageenan-induced pleurisy, CAY10606 significantly reduces both LT biosynthesis and the inflammatory reaction.