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ChemicalBook >> CAS DataBase List >> CYM50179

CYM50179

CYM50179 price.
  • $32 - $1420
  • Product name: CYM50179
  • CAS: 1355026-47-9
  • MF: C13H9Br2Cl2NO2
  • MW: 441.93006
  • EINECS:
  • MDL Number:MFCD26793887
  • Synonyms:2,6-Dibromo-3-[2-(2,4-dichlorophenoxy)ethoxy]-pyridine;CYM 50179;CYM50179;ML-178;CYM 50179 >=98% (HPLC);Pyridine, 2,6-dibromo-3-[2-(2,4-dichlorophenoxy)ethoxy]-;LPL Receptor,CYM 50179,Inhibitor,ML 178,autoimmune diseases,ML178,hrombocytopenia,CYM-50179,Lysophospholipid Receptor,viral infections,inhibit
7 prices
Selected condition:
Brand
  • AK Scientific
  • ApexBio Technology
  • Cayman Chemical
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 250mg
  • ManufacturerAK Scientific
  • Product number3734DF
  • Product description2,6-Dibromo-3-[2-(2,4-dichlorophenoxy)ethoxy]pyridine
  • Packaging5mg
  • Price$193
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4287
  • Product descriptionML-178
  • Packaging25mg
  • Price$390
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number18527
  • Product descriptionML-178 ≥95%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18527
  • Product descriptionML-178 ≥95%
  • Packaging5mg
  • Price$86
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18527
  • Product descriptionML-178 ≥95%
  • Packaging10mg
  • Price$153
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18527
  • Product descriptionML-178 ≥95%
  • Packaging25mg
  • Price$343
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberM425180
  • Product descriptionML-178
  • Packaging250mg
  • Price$1420
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 3734DF 2,6-Dibromo-3-[2-(2,4-dichlorophenoxy)ethoxy]pyridine 5mg $193 2021-12-16 Buy
ApexBio Technology C4287 ML-178 25mg $390 2021-12-16 Buy
Cayman Chemical 18527 ML-178 ≥95% 1mg $32 2024-03-01 Buy
Cayman Chemical 18527 ML-178 ≥95% 5mg $86 2024-03-01 Buy
Cayman Chemical 18527 ML-178 ≥95% 10mg $153 2024-03-01 Buy
Cayman Chemical 18527 ML-178 ≥95% 25mg $343 2024-03-01 Buy
TRC M425180 ML-178 250mg $1420 2021-12-16 Buy

Properties

storage temp. :-20°C
solubility :DMSO: soluble15mg/mL, clear
form :powder
color :white to beige

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger GHS hazard pictograms P280, P305+P351+P338, P310
H413 May cause long lasting harmful effects to aquatic life Hazardous to the aquatic environment, long-term hazard Category 4
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Sphingosine-1-phosphate (S1P) is an extracellular lipid mediator whose major effects are mediated through four of the S1P receptors (S1P1/EDG-1, S1P2/EDG-5, S1P3/EDG-3, S1P4/EDG-6, and S1P5/EDG-8). Binding of S1P to S1P4 activates ERK, MAPK, and PLC downstream signal transduction pathways. ML-178 activates S1P4 with an EC50 value of 46.3 nM and is inactive against S1P1, S1P2, S1P3, and S1P5 (EC50s = >50 μM) and has no effect against a panel of additional receptors, transporters, and ion channels.

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