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ChemicalBook >> CAS DataBase List >> EFT-508

EFT-508

EFT-508 price.
  • $68 - $1800
  • Product name: EFT-508
  • CAS: 1849590-01-7
  • MF: C17H20N6O2
  • MW: 340.38
  • EINECS:-0
  • MDL Number:MFCD30489732
  • Synonyms:EFT-508;6'-[(6-Amino-4-pyrimidinyl)amino]-8'-methylspiro[cyclohexane-1,3'(2'H)-imidazo[1,5-a]pyridine]-1',5'-dione;eFT508 -MNK;6'-((6-aminopyrimidin-4-yl)amino)-8'-methyl-1'H-spiro[cyclohexane-1,3'-imidazo[1,5-a]pyridine]-1',5'(2'H)-dione;Tomivosertib eFT508;CS-2450;EFT 508;EFT-508;TOMIVOSERTIB;6-[(6-aminopyrimidin-4-yl)amino]-8-methylspiro[2H-imidazo[1,5-a]pyridine-3,1'-cyclohexane]-1,5-dione
21 prices
Selected condition:
Brand
  • AK Scientific
  • Apolloscientific
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 1g
  • ManufacturerAK Scientific
  • Product number3244EF
  • Product descriptionTomivosertib
  • Packaging10mg
  • Price$232
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBISN0203
  • Product descriptioneFT508
  • Packaging1mg
  • Price$138
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBISN0203
  • Product descriptioneFT508
  • Packaging5mg
  • Price$348
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBISN0203
  • Product descriptioneFT508
  • Packaging10mg
  • Price$508
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBE168437
  • Product descriptioneFT 508
  • Packaging10mg
  • Price$135
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBE168437
  • Product descriptioneFT 508
  • Packaging50mg
  • Price$472.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number21957
  • Product descriptioneFT508 ≥98%
  • Packaging1mg
  • Price$68
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21957
  • Product descriptioneFT508 ≥98%
  • Packaging5mg
  • Price$302
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21957
  • Product descriptioneFT508 ≥98%
  • Packaging10mg
  • Price$535
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21957
  • Product descriptioneFT508 ≥98%
  • Packaging25mg
  • Price$1002
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5841
  • Product descriptionTomivosertib 99.92%
  • Packaging1mg
  • Price$96
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5841
  • Product descriptionTomivosertib 99.92%
  • Packaging5mg
  • Price$252
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5841
  • Product descriptionTomivosertib 99.92%
  • Packaging10mg
  • Price$372
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5841
  • Product descriptionTomivosertib 99.92%
  • Packaging50mg
  • Price$1140
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5841
  • Product descriptionTomivosertib 99.92%
  • Packaging100mg
  • Price$1620
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD00007104
  • Product descriptioneFT508 97%
  • Packaging5mg
  • Price$146
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 3244EF Tomivosertib 10mg $232 2021-12-16 Buy
Apolloscientific BISN0203 eFT508 1mg $138 2021-12-16 Buy
Apolloscientific BISN0203 eFT508 5mg $348 2021-12-16 Buy
Apolloscientific BISN0203 eFT508 10mg $508 2021-12-16 Buy
Biosynth Carbosynth BE168437 eFT 508 10mg $135 2021-12-16 Buy
Biosynth Carbosynth BE168437 eFT 508 50mg $472.5 2021-12-16 Buy
Cayman Chemical 21957 eFT508 ≥98% 1mg $68 2024-03-01 Buy
Cayman Chemical 21957 eFT508 ≥98% 5mg $302 2024-03-01 Buy
Cayman Chemical 21957 eFT508 ≥98% 10mg $535 2024-03-01 Buy
Cayman Chemical 21957 eFT508 ≥98% 25mg $1002 2024-03-01 Buy
ChemScene CS-5841 Tomivosertib 99.92% 1mg $96 2021-12-16 Buy
ChemScene CS-5841 Tomivosertib 99.92% 5mg $252 2021-12-16 Buy
ChemScene CS-5841 Tomivosertib 99.92% 10mg $372 2021-12-16 Buy
ChemScene CS-5841 Tomivosertib 99.92% 50mg $1140 2021-12-16 Buy
ChemScene CS-5841 Tomivosertib 99.92% 100mg $1620 2021-12-16 Buy
Crysdot CD00007104 eFT508 97% 5mg $146 2021-12-16 Buy

Properties

Melting point :>300°C
Boiling point :735.6±60.0 °C(Predicted)
Density :1.43±0.1 g/cm3(Predicted)
storage temp. :Refrigerator, under inert atmosphere
solubility :DMSO (Slightly, Heated), Methanol (Very Slightly)
pka :13.77±0.60(Predicted)
form :Solid
color :Pale Yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

eFT508 is a potent inhibitor of MAPK interacting protein kinases (MNK) 1 and 2 (IC50s = <10 nM). It inhibits phosphorylation of eukaryotic initiation factor 4E (eIF4E) with an IC50 value of <50 nM in a cellular signaling assay. eFT508 has a half-life of 5.3 hours in rats.

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