FzM1
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- $37 - $547
- Product name: FzM1
- CAS: 1680196-54-6
- MF: C21H16N2O2S
- MW: 360.43
- EINECS:
- MDL Number:MFCD29079017
- Synonyms:FzM1;FzM1 (Fzd4 modulator FzM1;FzM1 >=98% (HPLC);Urea, N-[3-hydroxy-5-(2-thienyl)phenyl]-N'-2-naphthalenyl-;N-[3-hydroxy-5-(2-thienyl)phenyl]-N'-2-naphthalenyl-urea
5 prices
Selected condition：
Brand
- AK Scientific
- Cayman Chemical
Package
- 500μg
- 1mg
- 5mg
- 10mg
- 50mg
- ManufacturerAK Scientific
- Product numberSYN5597
- Product descriptionFzM1
- Packaging10mg
- Price$160
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberSYN5597
- Product descriptionFzM1
- Packaging50mg
- Price$547
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number19074
- Product descriptionFzM1 ≥95%
- Packaging500μg
- Price$37
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number19074
- Product descriptionFzM1 ≥95%
- Packaging1mg
- Price$68
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number19074
- Product descriptionFzM1 ≥95%
- Packaging5mg
- Price$118
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | SYN5597 | FzM1 | 10mg | $160 | 2021-12-16 | Buy |
| AK Scientific | SYN5597 | FzM1 | 50mg | $547 | 2021-12-16 | Buy |
| Cayman Chemical | 19074 | FzM1 ≥95% | 500μg | $37 | 2024-03-01 | Buy |
| Cayman Chemical | 19074 | FzM1 ≥95% | 1mg | $68 | 2024-03-01 | Buy |
| Cayman Chemical | 19074 | FzM1 ≥95% | 5mg | $118 | 2024-03-01 | Buy |
Properties
Boiling point :518.3±50.0 °C(Predicted)
Density :1.401±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 12 mg/ml; DMF:PBS (pH 7.2)(1:3): 0.2 mg/ml; DMSO: 10 mg/ml
form :A crystalline solid
pka :9.42±0.10(Predicted)
color :White to light brown
Density :1.401±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 12 mg/ml; DMF:PBS (pH 7.2)(1:3): 0.2 mg/ml; DMSO: 10 mg/ml
form :A crystalline solid
pka :9.42±0.10(Predicted)
color :White to light brown
Safety Information
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| Signal word: | Warning | |||||||
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Description
Wnt signaling proteins are small secreted proteins that are active in embryonic development, tissue homeostasis, and tumorigenesis. Wnt proteins initiate cell signaling by binding Frizzled (Fz) receptors, a family of G protein-coupled receptors. FzM1 is an allosteric ligand of Fz4. At 10 μM, it inhibits nuclear translocation of β-catenin in U87MG glioma cells treated with lithium chloride, a GSK3 inhibitor that enhances the Wnt canonical signaling pathway. FzM1 impairs the ability of U87MG cells to form neurospheres in culture and stimulates the differentiation of Caco-2 epithelial colorectal adenocarcinoma cells.Suppliers and manufacturers
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